2-Fluoro-6-nitro-N-phenylbenzamide(CAS: 870281-83-7)

2-Fluoro-6-nitro-N-phenylbenzamide (CAS: 870281-83-7) is a crystalline solid with a molecular weight of approximately 290.13 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. The compound is moderately reactive, particularly with reducing agents, and exhibits weak acidic behavior due to the nitro group. It is stable under normal conditions but should be stored in a dry, cool place to prevent hydrolysis.

2-Fluoro-6-nitro-N-phenylbenzamide (CAS: 870281-83-7) can be synthesized via a multi-step process, starting with the nitration of 2-fluorobenzamide. The nitro group is introduced using a mixture of fuming nitric acid and sulfuric acid. Subsequently, the phenyl substituent is introduced via coupling with phenyl isocyanate in the presence of a base like triethylamine. The reaction is typically carried out in an organic solvent such as dichloromethane, with yields ranging from 60-80%.

2-Fluoro-6-nitro-N-phenylbenzamide (CAS: 870281-83-7) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a precursor for the production of functional polymers, and in sensor technology for developing sensors that can detect specific chemical compounds. Additionally, it is used in some semiconductor applications due to its electronic properties.

When handling 2-Fluoro-6-nitro-N-phenylbenzamide (CAS: 870281-83-7), it is crucial to follow standard safety protocols. It should be stored in a cool, dry place, away from sources of heat and light. Gloves and safety goggles should be worn at all times. The compound should be handled in a well-ventilated fume hood to minimize exposure to fumes. In case of a spill, the area should be flushed with water, and the material should be collected and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.