5-Bromo-2-fluoronicotinaldehyde

Basic Information

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CAS Number

875781-15-0

Molecular Formula

C6H3BrFNO

Molecular Weight

204 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

258.2℃ at 760 mmHg

Density

1.778

Flash Point

109.936℃

Refractive Index

1.591

SMILES

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C1=C(C=NC(=C1C=O)F)Br

InChI

InChI=1S/C6H3BrFNO/c7-5-1-4(3-10)6(8)9-2-5/h1-3H

InChIKey

MUYVOGAJRCBWCY-UHFFFAOYSA-N

LogP

1.7956999999999999

Topological Polar Surface Area

29.96 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

133

Synonyms & References

English

5-BROMO-2-FLUOROPYRIDINE-3-CARBOXALDEHYDE
PB29718
5-bromo-2-fluoronicotinaldehyde
5-Bromo-2-fluoro-pyridine-3-carbaldehyde
BCP31457
FT-0660367
3-PYRIDINECARBOXALDEHYDE, 5-BROMO-2-FLUORO-
875781-15-0
PS-8160
EN300-177620
AM20061819
CS-W019631
MFCD09842440
SCHEMBL741314
SY016108
DTXSID10670233
SB00007
AKOS015853510
5-Bromo-2-fluoro-3-pyridinecarboxaldehyde
AC-9440
MUYVOGAJRCBWCY-UHFFFAOYSA-N
5-bromo-2-fluoropyridine-3-carbaldehyde
5-Bromo-2-fluoro-3-formylpyridine
Q-101260
5-Bromo-2-fluoropyridine-3-carboxaldehyde
3-Pyridinecarboxaldehyde,5-bromo-2-fluoro-
5-Bromo-2-fluoronicotinaldehyde
PubChem17162
KSC495S8T
STL556104
RW2859

MDL Number

MFCD09842440

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Bromo-2-fluoronicotinaldehyde (CAS: 875781-15-0)?

5-Bromo-2-fluoronicotinaldehyde (CAS: 875781-15-0) is a white crystalline solid with a molecular weight of 230.03 g/mol. It has a moderate solubility in common organic solvents like ethanol and acetonitrile. The compound is known for its reactivity towards nucleophilic substitution and electrophilic aromatic substitution reactions. It is also sensitive to moisture and should be stored in a dry environment.

How is 5-Bromo-2-fluoronicotinaldehyde (CAS: 875781-15-0) typically synthesized?

5-Bromo-2-fluoronicotinaldehyde (CAS: 875781-15-0) is typically synthesized via a bromination and fluorination reaction of nicotinaldehyde. This process involves treating nicotinaldehyde with bromine and fluorine under controlled conditions using appropriate catalysts to achieve the desired selectivity and yield. The synthesis is complex and requires careful handling to avoid side reactions.

What industries use 5-Bromo-2-fluoronicotinaldehyde (CAS: 875781-15-0)?

5-Bromo-2-fluoronicotinaldehyde (CAS: 875781-15-0) is used in various industries, particularly in the pharmaceutical sector for the synthesis of drugs, and in the polymer industry for developing novel materials. It is also utilized in the electronics industry for the production of semiconductors and in the sensor industry for creating sensitive detection devices.

What precautions should be taken when handling 5-Bromo-2-fluoronicotinaldehyde (CAS: 875781-15-0)?

When handling 5-Bromo-2-fluoronicotinaldehyde (CAS: 875781-15-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents and handled according to the safety data sheet (SDS). This compound is sensitive to moisture and should be stored in a dry, cool place away from direct sunlight.