2,5-Dichloro-N-[2-(isopropylsulfanyl)phenyl]-4-pyrimidinamine(CAS: 1632485-14-3)

2,5-Dichloro-N-[2-(isopropylsulfanyl)phenyl]-4-pyrimidinamine (CAS: 1632485-14-3) is a solid with a molecular weight of approximately 357.06 g/mol. It has a crystalline form and a high melting point, around 200°C. It is slightly soluble in water but soluble in organic solvents like DMSO and DMF. This compound is reactive towards nucleophiles and shows potential for substitution reactions.

2,5-Dichloro-N-[2-(isopropylsulfanyl)phenyl]-4-pyrimidinamine is typically synthesized via a multistep process involving the reaction of 2-chloro-4-pyrimidinamine with 2-(isopropylthio)benzaldehyde. The synthesis usually involves a palladium-catalyzed cross-coupling reaction, followed by a nucleophilic substitution step. The yield is around 70-80%, and the purity is above 95%.

2,5-Dichloro-N-[2-(isopropylsulfanyl)phenyl]-4-pyrimidinamine (CAS: 1632485-14-3) is primarily used in the pharmaceutical industry for the development of new drugs, particularly in antiviral and anticancer drug research. It may also find applications in the sensor and semiconductor industries due to its specific chemical functionality.

When handling 2,5-Dichloro-N-[2-(isopropylsulfanyl)phenyl]-4-pyrimidinamine (CAS: 1632485-14-3), it is essential to work in a well-ventilated area or a fume hood. Wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Spills should be carefully cleaned up using appropriate chemical spill kits. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.