N-(2,3-Dimethylphenyl)-3-hydroxy-2-naphthamide

Basic Information

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CAS Number

6358-02-7

Molecular Formula

C19H17NO2

Molecular Weight

291.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

224-225 ºC

SMILES

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CC1=C(C(=CC=C1)NC(=O)C2=CC3=CC=CC=C3C=C2O)C

InChI

InChI=1S/C19H17NO2/c1-12-6-5-9-17(13(12)2)20-19(22)16-10-14-7-3-4-8-15(14)11-18(16)21/h3-11,21H,1-2H3,(H,20,22)

InChIKey

QQJZWTLAVYMEEW-UHFFFAOYSA-N

LogP

4.414540000000003

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

397

Synonyms & References

English

CCG-276019
2-Naphthalenecarboxamide, N-(2,3-dimethylphenyl)-3-hydroxy-
6358-02-7
Oprea1_015894
N-(2,3-Dimethylphenyl)-3-hydroxy-2-naphthamide
AKOS000579178
N-(2,3-dimethylphenyl)-3-hydroxynaphthalene-2-carboxamide
Oprea1_728952
2-Amino-4-chloro-5-nitrophenol
2-Naphtho-2',3'-xylidide,3-hydroxy- (8CI)

MDL Number

MFCD00010300

FAQ

What are the physical and chemical properties of N-(2,3-Dimethylphenyl)-3-hydroxy-2-naphthamide (CAS: 6358-02-7)?

N-(2,3-Dimethylphenyl)-3-hydroxy-2-naphthamide is a crystalline solid with a molecular weight of approximately 325.33 g/mol. It has a solubility of about 0.3 g/L in water. The compound is moderately reactive towards bases and exhibits good stability towards acids. It can undergo substitution and condensation reactions under certain conditions.

How is N-(2,3-Dimethylphenyl)-3-hydroxy-2-naphthamide (CAS: 6358-02-7) typically synthesized?

N-(2,3-Dimethylphenyl)-3-hydroxy-2-naphthamide can be synthesized by reacting 2-hydroxy-3-naphthoic acid with 2,3-dimethylphenylamine. The reaction is typically carried out in the presence of a suitable base such as sodium hydroxide, with a yield of around 85%. The reaction is selective and proceeds efficiently under mild conditions.

What industries use N-(2,3-Dimethylphenyl)-3-hydroxy-2-naphthamide (CAS: 6358-02-7)?

N-(2,3-Dimethylphenyl)-3-hydroxy-2-naphthamide is primarily used in the pharmaceutical industry for the synthesis of certain organic compounds. It also finds applications in the polymer industry as a precursor for the production of advanced materials. Additionally, it is used in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling N-(2,3-Dimethylphenyl)-3-hydroxy-2-naphthamide (CAS: 6358-02-7)?

When handling N-(2,3-Dimethylphenyl)-3-hydroxy-2-naphthamide, it is essential to wear proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.