Angiotensin II 5-valine

Basic Information

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CAS Number

58-49-1

Molecular Formula

C49H69N13O12

Molecular Weight

1032.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC(C)C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C(C)C)C(=O)NC(CC2=CN=CN2)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N

InChI

InChI=1S/C49H69N13O12/c1-26(2)39(60-42(67)33(12-8-18-54-49(51)52)56-41(66)32(50)23-38(64)65)45(70)57-34(20-29-14-16-31(63)17-15-29)43(68)61-40(27(3)4)46(71)58-35(22-30-24-53-25-55-30)47(72)62-19-9-13-37(62)44(69)59-36(48(73)74)21-28-10-6-5-7-11-28/h5-7,10-11,14-17,24-27,32-37,39-40,63H,8-9,12-13,18-23,50H2,1-4H3,(H,53,55)(H,56,66)(H,57,70)(H,58,71)(H,59,69)(H,60,67)(H,61,68)(H,64,65)(H,73,74)(H4,51,52,54)/t32-,33-,34-,35-,36-,37-,39-,40-/m0/s1

InChIKey

NLPUTBDZNNXHCO-CGHBYZBKSA-N

LogP

-1.7048000000000068

Topological Polar Surface Area

408.8399999999999 Å²

Hydrogen Bond Donor/Acceptor

16 / 25

Complexity

1960

Synonyms & References

English

F85422
CHEMBL216830
[Asp1-Arg2-Val3-Tyr4-Val5-His6-Pro7-Phe8](angiotensin II)
BDBM50048128
Valine angiotensin II
HY-P0108
Asp-Arg-Val-Tyr-Val-His-Pro-Phe (Angiotensin II)
[Val5] - ANGIOTENSIN II
CS-5786
58-49-1
Angiotensin II 5-valine
(2S,5S,8S,11S,14S,17S)-2-((1H-imidazol-5-yl)methyl)-17-amino-1-((S)-2-(((S)-1-carboxy-2-phenylethyl)carbamoyl)pyrrolidin-1-yl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-5,11-diisopropyl-1,4,7,10,13,16-hexaoxo-3,6,9,12,15-pentaazanonadecan-19-oic acid
(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxy-2-phenylethyl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Asp-Arg-Val-Tyr-Val-His-Pro-Phe
MS-31880
(Val5)-Angiotensin II (H-L-Asp-L-Arg-L-Val-L-Tyr-L-Val-L-His-L-Pro-L-Phe-OH)
CHEBI:48434
bovine angiotensin II
(Val5)-Angiotensin II H-Asp-Arg-Val-Tyr-Val-His-Pro-Phe-OH
Q27121202
AspArgValTyrValHisProPh
MFCD00167495
L-alpha-aspartyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-L-histidyl-L-prolyl-L-phenylalanine
Val(5)-angiotensin II
Angiotensin acetate
[VAL5]-ANGIOTENSIN II
[VAL5] ANGIOTENSIN II HUMAN
ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE
DRVYVHPF
L-ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE
H-ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH

MDL Number

MFCD00167495

FAQ

What is Angiotensin II 5-valine (CAS: 58-49-1)?

Angiotensin II 5-valine (CAS: 58-49-1) is a chemically modified form of angiotensin II, which is a potent vasoconstrictor and plays a crucial role in the renin-angiotensin-aldosterone system. It is often used in research for studying cardiovascular effects.

What are the main uses of Angiotensin II 5-valine (CAS: 58-49-1)?

Angiotensin II 5-valine (CAS: 58-49-1) is primarily used in pharmaceutical research to investigate the effects of angiotensin II modifications on cardiovascular systems. It is also used in academic and industrial settings for research purposes.

Is Angiotensin II 5-valine (CAS: 58-49-1) safe?

Angiotensin II 5-valine (CAS: 58-49-1) is generally safe when handled according to standard laboratory procedures. However, it is important to follow all safety guidelines, such as wearing appropriate personal protective equipment (PPE) and storing it in a cool, dry place away from light.

How should Angiotensin II 5-valine (CAS: 58-49-1) be stored?

Angiotensin II 5-valine (CAS: 58-49-1) should be stored in a cool, dry place, protected from light, and at a temperature not exceeding 25°C. It should be kept in a tightly sealed container to prevent degradation.