Methyl 2-amino-4-(4-chlorophenyl)-5-pyrimidinecarboxylate
CAS Number:
1133115-56-6
Molecular Formula:
C12H10ClN3O2
Pd/P/dba-Promoted cascade annulations to produce fused medium-sized sulfoximine polyheterocycles
Literature Information
Publication Date
2019-08-29
DOI
10.1039/C9QO00880B
Impact Factor
5.281
Authors
Xiaoyan Chen, Hao Zhou, Zhiyuan Chen
View Original
Abstract
The Pd-catalyzed multicomponent reactions of NH-sulfoximine, aryl iodide and norbornadiene (NBD) are reported to chemoselectively produce fused medium-sized sulfoximine polyheterocycles in good to excellent yields. The addition of the dibenzylideneacetone (dba) ligand was found to be useful for this tandem annulation reaction. Under the optimized conditions, a broad range of 3D-type heterocyclic sulfoximines with good functional group tolerance were generated.
Recommended Journals
Drug Discovery Today
Russian Journal of Bioorganic Chemistry
Current Opinion in Solid State & Materials Science
Russian Journal of General Chemistry
Nature Medicine
Journal of Saudi Chemical Society
Crystallography Reports
Russian Journal of Organic Chemistry
Organic Process Research & Development
Journal of Natural Medicines
Related Literature
Ground and excited state properties of furanoflavylium derivatives
Alfonso Alejo-Armijo, Nuno Basílio, Adilson A. Freitas, António L. Maçanita, João C. Lima, A. Jorge Parola, Fernando Pina
2019-09-13
Paper
DOI: 10.1039/C9CP04917G
Coalescence and wetting mechanism of Al droplets on different types of carbon for developing wettable cathodes: a molecular dynamics simulation
Xiaojun Lv, Chaohong Guan, Zexun Han, Chang Chen, Qidong Sun
2019-09-06
Paper
DOI: 10.1039/C9CP03673C
Combining site-directed spin labeling in vivo and in-cell EPR distance determination
Pia Widder, Julian Schuck, Daniel Summerer, Malte Drescher
2020-02-18
Communication
DOI: 10.1039/C9CP05584C
Correction: Predictable spectroscopic properties of type-II ZnTe/CdSe nanocrystals and electron/hole quenching
Tongqing Long, Jun Cao
2020-03-03
Correction
DOI: 10.1039/D0CP90055A
Boron-based inorganic heterocyclic clusters: electronic structure, chemical bonding, aromaticity, and analogy to hydrocarbons
Lin-Yan Feng, Rui Li, Hua-Jin Zhai
2019-07-04
Perspective
DOI: 10.1039/C9CP03254A
Water binding to FeIII hemes studied in a cooled ion trap: characterization of a strong ‘weak’ ligand
Mohammad Aarabi, Satchin Soorkia, Gilles Grégoire, Aurélien de la Lande, Benoît Soep, Reza Omidyan, Niloufar Shafizadeh
2019-09-02
Paper
DOI: 10.1039/C9CP03608C
CO2 as an auto-catalyst for the oxidation of CO by a Criegee intermediate (CH2OO)
Amit Kumar, Pradeep Kumar
2020-03-06
Paper
DOI: 10.1039/D0CP00027B
A theoretical investigation on boron–ligand cooperation to activate molecular hydrogen by a frustrated Lewis pair and subsequent reduction of carbon dioxide
Manas Ghara, Sudip Pan
2019-09-05
Paper
DOI: 10.1039/C9CP03756J
Breakdown of continuum model for water transport and desalination through ultrathin graphene nanopores: insights from molecular dynamics simulations
2019-09-05
Paper
DOI: 10.1039/C9CP04364K
You might also like
Compound Q&A
Is 6-(3-Fluorophenyl)picolinic acid (CAS: 887982-40-3) safe?
6-(3-Fluorophenyl)picolinic acid is generally considered safe for laboratory use...
887982-40-36-(3-Fluorophenyl)pi...
Compound Q&A
What industries use (3R)-3-Pyrrolidinol (CAS: 2799-21-5)?
(3R)-3-Pyrrolidinol is used in the pharmaceutical industry as a precursor for dr...
2799-21-5(3R)-3-Pyrrolidinol
Compound Q&A
What precautions should be taken when handling (4R,5R)-4,5-Diethoxycarbonyl-2,2-dimethyldioxolane (CAS: 59779-75-8)?
When handling (4R,5R)-4,5-Diethoxycarbonyl-2,2-dimethyldioxolane (CAS: 59779-75-...
59779-75-8(4R,5R)-4,5-Diethoxy...
Compound Q&A
How is 1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone (CAS: 90734-71-7) typically synthesized?
1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone is often synthesized via a mult...
90734-71-71-(6-Chloroimidazo[1...
Compound Q&A
What is the market or research trend for N-Ethyl-3,4-dimethylbenzylamine (CAS: 39180-83-1)?
The market for N-Ethyl-3,4-dimethylbenzylamine (CAS: 39180-83-1) remains steady,...
39180-83-1N-Ethyl-3,4-dimethyl...
Compound Q&A
What is Tert-butyl 3-(pyrrolidin-1-yl)azetidine-1-carboxylate (CAS: 1019008-21-9)?
Tert-butyl 3-(pyrrolidin-1-yl)azetidine-1-carboxylate is a chemical compound wit...
1019008-21-9Tert-butyl 3-(pyrrol...
Compound Q&A
What regulatory guidelines apply to 1-Bromo-3-chloro-2,4-dimethoxybenzene (CAS: 1228956-93-1)?
1-Bromo-3-chloro-2,4-dimethoxybenzene (CAS: 1228956-93-1) falls under the classi...
1228956-93-11-Bromo-3-chloro-2,4...
Compound Q&A
Is 8-Bromo-2-methyl-3,4-dihydroisoquinolin-1(2H)-one (CAS: 1368622-07-4) safe?
The safety of 8-Bromo-2-methyl-3,4-dihydroisoquinolin-1(2H)-one (CAS: 1368622-07...
1368622-07-48-Bromo-2-methyl-3,4...
Compound Q&A
Is Benzyl [(3S)-2,6-dioxo-3-piperidinyl]carbamate (CAS: 22785-43-9) safe?
Benzyl [(3S)-2,6-dioxo-3-piperidinyl]carbamate is generally safe when handled wi...
22785-43-9Benzyl [(3S)-2,6-dio...
Compound Q&A
How should 1-{[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfonyl}pyrrolidine (CAS: 928657-21-0) be stored?
1-{[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfonyl}pyrrolidine s...
928657-21-01-{[4-(4,4,5,5-Tetra...
Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
(S)-1-(3-(Benzyloxy)phenyl)-3-(dimethylamino)-2-methylpropan-1-one (2r,3r)-2,3-bis(benzoyloxy)succinate
CAS Number:
1004315-81-4
Molecular Formula:
C37H37NO10
![1-Benzyl-1,7-diazaspiro[4.4]nonane dihydrochloride structure](https://static.chemtradehub.com/structs/115/1159822-71-5-0320.webp "1-Benzyl-1,7-diazaspiro[4.4]nonane dihydrochloride structure")
1-Benzyl-1,7-diazaspiro[4.4]nonane dihydrochloride
CAS Number:
1159822-71-5
Molecular Formula:
C14H22Cl2N2
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.