1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone

Basic Information

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CAS Number

90734-71-7

Molecular Formula

C8H6ClN3O

Molecular Weight

195.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Solid

SMILES

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CC(=O)C1=CN=C2N1N=C(C=C2)Cl

InChI

InChI=1S/C8H6ClN3O/c1-5(13)6-4-10-8-3-2-7(9)11-12(6)8/h2-4H,1H3

InChIKey

ODNBVEIAQAZNNM-UHFFFAOYSA-N

LogP

1.5852999999999997

Topological Polar Surface Area

47.260000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

223

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone
1-(6-CHLOROIMIDAZO[1,2-B]PYRIDAZIN-3-YL)-ETHANONE
Ethanone,1-(6-chloroimidazo[1,2-b]pyridazin-3-yl)-
3-Acetyl-6-chloroimidazo[1,2-b]pyridazine
Ethanone, 1-(6-chloroimidazo[1,2-b]pyridazin-3-yl)-
1-{6-chloroimidazo[1,2-b]pyridazin-3-yl}ethan-1-one
1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethan-1-one
KSC496S6R
ODNBVEIAQAZNNM-UHFFFAOYSA-N
RW3143
FCH887301
TRA0069310
SY004908
BR-8
1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone (ACI)
Imidazo[1,2-b]pyridazine, ethanone deriv. (ZCI)
1-[6-Chloroimidazo[1,2-b]pyridazin-3-yl]ethan-1-one
1-{6-CHLOROIMIDAZO[1,2-B]PYRIDAZIN-3-YL}ETHANONE
SCHEMBL430630
EN300-1723200
3-ACETYL-6-CHLOROIMIDAZO[1,2-B]PYRIDAZINE
AC-5172
3-Acetyl-6-chloroimidazo[1 pound not2-b]pyridazine
CS-0092052
MFCD11044766
1-(6-chloro-imidazo[1,2-b]pyridazin-3-yl)-ethanone
AKOS006309965
1-(6-chloro-imidazo[1,2-b]pyridazin-3-yl)ethanone
Z1198307496
6-chloro-imidazo[1,2-b]pyridazine-3-yl-ethanone
DB-078788

MDL Number

MFCD11044766

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone (CAS: 90734-71-7)?

1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone is a crystalline solid with a molecular weight of approximately 292.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like DMSO and DMF. This compound is highly reactive and can undergo various chemical transformations under specific conditions.

How is 1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone (CAS: 90734-71-7) typically synthesized?

1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone is often synthesized via a multi-step process involving the condensation of 6-chloroimidazo[1,2-b]pyridazine with acetyl chloride, followed by reduction of the ketone functionality. The synthesis typically requires the use of a catalyst such as sodium triacetoxyborohydride, and the process achieves good yield with high selectivity.

What industries use 1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone (CAS: 90734-71-7)?

1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone is utilized in the pharmaceutical industry for its potential as an intermediate in the synthesis of bioactive compounds. It also finds applications in the development of sensors and materials for semiconductors.

What precautions should be taken when handling 1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone (CAS: 90734-71-7)?

When handling 1-(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethanone, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to prevent inhalation of fumes. In case of a spill, absorb with paper towels and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.