An ultrasensitive electrochemiluminescence biosensor for nuclear factor kappa B p50 based on the proximity hybridization-induced hybridization chain reaction

Literature Information

Publication Date 2019-10-10
DOI 10.1039/C9CC06210F
Impact Factor 6.222
Authors

Xiaocui Huang, Ying Zhang, Wen Xu, Wei Xu, Longhua Guo, Bin Qiu, Zhenyu Lin


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Abstract

Nuclear factor kappa B p50 (NF-κB p50) induces various biological processes. In this study, a highly selective and sensitive electrochemiluminescence (ECL) biosensor for the detection of NF-κB p50 has been developed, which combines the high selectivity of the proximity hybridization assay (PHA) with the high efficiency of the hybridization chain reaction (HCR).

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