Apalutamide Impurity 47

Basic Information

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CAS Number

99368-66-8

Molecular Formula

C6H3F3N2O3

Molecular Weight

208.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

158°C

Boiling Point

345.5°C at 760 mmHg

Density

1.61

Flash Point

108.2℃

SMILES

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C1=C(C(=O)NC=C1[N+](=O)[O-])C(F)(F)F

InChI

InChI=1S/C6H3F3N2O3/c7-6(8,9)4-1-3(11(13)14)2-10-5(4)12/h1-2H,(H,10,12)

InChIKey

BHUILUYFGJBXHQ-UHFFFAOYSA-N

LogP

2.23740

Complexity

350

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5-nitro-3-(trifluoromethyl)pyridin-2-ol
GS-6645
PS-6647
AKOS025117306
RB1055
5-Nitro-3-trifluoromethyl-pyridin-2-ol
BCP10216
AC-22598
FT-0612557
5-Nitro-3-trifluoromethyl-pyridin-2-ol;3-NITRO-5-TRIFLUOROMETHYL-2-PYRIDINONE
5-nitro-3-(trifluoromethyl)-2(1H)-Pyridinone
DTXSID10379375
EN300-109594
Z1269121238
AM20070177
5-Nitro-3-(trifluoromethyl)pyridin-2-ol, 95%
AKOS015856409
MB01148
J-509651
2-HYDROXY-5-NITRO-3-(TRIFLUOROMETHYL)PYRIDINE
A5939
5-Nitro-3-(trifluoromethyl)pyridin-2(1H)-one
99368-66-8
2(1H)-Pyridinone, 5-nitro-3-(trifluoromethyl)-
MFCD00276983
SCHEMBL909616
SCHEMBL14959667
CS-M3575
5-nitro-3-(trifluoromethyl)-1H-pyridin-2-one
SY018982
2(1H)-Pyridinone,5-nitro-3-(trifluoromethyl)-

MDL Number

MFCD00276983

Customs Code

2933399090

FAQ

What is Apalutamide Impurity 47 (CAS: 99368-66-8)?

Apalutamide Impurity 47, with the CAS number 99368-66-8, is a chemical compound identified as an impurity in the pharmaceutical drug Apalutamide. It is typically characterized by its molecular structure, which is related to the parent drug but differs in specific functional groups. This compound is often analyzed during quality control processes to ensure the purity and safety of the final medication.

What are the main uses of Apalutamide Impurity 47 (CAS: 99368-66-8)?

Apalutamide Impurity 47 is primarily used in pharmaceutical research and development to identify and quantify impurities in Apalutamide, a medication used for treating prostate cancer. It may also be relevant in analytical chemistry for method validation, stability testing, and ensuring compliance with regulatory standards in drug manufacturing.

Is Apalutamide Impurity 47 (CAS: 99368-66-8) safe?

Apalutamide Impurity 47 is generally considered safe when handled properly, but it is important to follow standard laboratory safety protocols. As an impurity, it may have potential toxicity depending on its structure and concentration. Proper protective equipment, such as gloves and goggles, should be used during handling, and it should be stored under controlled conditions to prevent contamination or degradation.

How should Apalutamide Impurity 47 (CAS: 99368-66-8) be stored?

Apalutamide Impurity 47 should be stored in a cool, dry, and dark place, away from moisture and light. It is recommended to keep it in a sealed container at a temperature between 2°C to 8°C to maintain stability. Avoid exposure to air and ensure proper labeling to prevent cross-contamination and ensure safe handling.