Diastereoselective construction of pyrrolo[2,1-a]isoquinoline-based bispirooxindoles through a three-component [3 + 2] cycloaddition
Literature Information
Publication Date
2018-08-03
DOI
10.1039/C8OB01493K
Impact Factor
3.876
Authors
Jiaomei Guo, Yang Zhao, Dongmei Fang, Qilin Wang, Zhanwei Bu
View Original
Abstract
An efficient three-component one-pot [3 + 2] cycloaddition of isatins, 1,2,3,4-tetrahydroisoquinolines and methyleneindolinones has been developed. This reaction proceeded in a highly diastereoselective manner to afford a wide range of pyrrolo[1,2-a]isoquinoline-based bispirooxindoles in up to 91% yields. Additionally, a gram-scale experiment and some chemical transformations were conducted.
Recommended Journals
Related Literature
Dicarboxylic acid-epoxy vitrimers: influence of the off-stoichiometric acid content on cure reactions and thermo-mechanical properties
Jonny J. Blaker, Constantinos Soutis, François Tournilhac, Matthieu Gresil
2020-06-17
Paper
DOI: 10.1039/D0PY00342E
Development of physical, mechanical, antibacterial and cell growth properties of poly(glycerol sebacate urethane) (PGSU) with helping of curcumin and hydroxyapatite nanoparticles
Vafa Fakhri, Aliakbar Jafari, Mir Alireza Shafiei, Mohammad Vahid Ehteshamfar, Shima Khalighiyan, Hadi Hosseini, Vahabodin Goodarzi, Frederik R. Wurm, Mehrdad Moosazadeh Moghaddam
2021-10-19
Paper
DOI: 10.1039/D1PY01040A
Photo-switchable smart superhydrophobic surface with controllable superwettability
Xiaoyan Yang, Haibao Jin, Xinfeng Tao, Binbin Xu, Shaoliang Lin
2021-08-25
Paper
DOI: 10.1039/D1PY00984B
Multi-responsive poly(oligo(ethylene glycol)methyl methacrylate)-co-poly(2-(diisopropylamino)ethyl methacrylate) hyperbranched copolymers via reversible addition fragmentation chain transfer polymerization
Dimitrios Selianitis, Stergios Pispas
2021-11-03
Paper
DOI: 10.1039/D1PY01320C
Impact of multi-vinyl taxogen dimensions on high molecular weight soluble polymer synthesis using transfer-dominated branching radical telomerisation
Oliver B. Penrhyn-Lowe, Sean Flynn, Savannah R. Cassin, Samuel Mckeating, Sarah Lomas, Stephen Wright, Pierre Chambon, Steve P. Rannard
2021-10-22
Paper
DOI: 10.1039/D1PY01103K
Impacts of performing electrolysis during organocatalyzed atom transfer radical polymerization
Daniel A. Corbin, Blaine G. McCarthy, Garret M. Miyake
2020-06-30
Paper
DOI: 10.1039/D0PY00643B
Divergence of polycondensation by a tandem reaction based on sequential conjugate substitutions
Keito Hagiwara
2020-07-08
Communication
DOI: 10.1039/D0PY00648C
Highly efficient terpolymerizations of ethylene/propylene/ENB with a half-titanocene catalytic system
Yi-Cong Wang, Pei-Yi Cheng, Zhi-Qian Zhang, Ke-Xin Fan, Rui-Qi Lu, Shu Zhang, Yi-Xian Wu
2021-10-29
Paper
DOI: 10.1039/D1PY01140E
Semiaromatic polyamides with enhanced charge carrier mobility
Bilal Özen, Nicolas Candau, Cansel Temiz, Ferdinand C. Grozema, Grégory Stoclet, Christopher J. G. Plummer, Holger Frauenrath
2021-11-10
Paper
DOI: 10.1039/D1PY01203G
Cross-linking approaches for block copolymer nano-assemblies via RAFT-mediated polymerization-induced self-assembly
Shenzhen Li, Guang Han
2020-06-09
Minireview
DOI: 10.1039/D0PY00627K
You might also like
Compound Q&A
What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?
N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...
52818-63-0N-(4-Methoxybenzyl)-...
Compound Q&A
What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?
When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...
1050507-06-6Ethyl 4-(2-chlorophe...
Compound Q&A
What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?
Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...
628-39-7Diethyldiselane
Compound Q&A
What is the market or research trend for oxocopper (CAS: 12053-18-8)?
The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...
12053-18-8oxocopper; oxo-(oxoc...
Compound Q&A
What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?
The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...
1268519-54-55-{[(2-Methyl-2-prop...
Compound Q&A
What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?
2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...
35981-63-62-(1-Pyrrolidinyl)-4...
Compound Q&A
What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?
2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...
91556-75-12-(3-Pyridinyl)-1-az...
Compound Q&A
How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?
(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...
129704-91-2(S)-Alpha-allyl-prol...
Compound Q&A
What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?
3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...
4857-42-53-Methyl-1,2-oxazole...
Compound Q&A
How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?
Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...
1281816-04-3Lys-SMCC-DM1
Source Journal
Organic & Biomolecular Chemistry
CiteScore:
3.4
Self-citation Rate:
10.3%
Articles per Year:
1041
Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.
Recommended Compounds
![1-{3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl}-2,3-dihydroxy-1-propanone structure](https://static.chemtradehub.com/structs/122/1226872-27-0-e037.webp "1-{3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl}-2,3-dihydroxy-1-propanone structure")
1-{3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl}-2,3-dihydroxy-1-propanone
CAS Number:
1226872-27-0
Molecular Formula:
C25H26N6O4
N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine hydrochloride (1:1)
CAS Number:
1188266-11-6
Molecular Formula:
C18H20ClNOS
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.