![5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine structure](https://static.chemtradehub.com/structs/865/865362-74-9-0091.webp "5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine structure")
5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine
CAS Number:
865362-74-9
Molecular Formula:
C18H13N7
Polymersomes enhance the immunogenicity of influenza subunit vaccine
Literature Information
Publication Date
2011-03-29
DOI
10.1039/C1PY00010A
Impact Factor
5.582
Authors
Christophe Barnier Quer, Hana Robson Marsden, Stefan Romeijn, Harshal Zope, Alexander Kros, Wim Jiskoot
View Original
Abstract
In this study poly(γ-benzyl-L-glutamate)-K (PBLG50-K) polymersomes are tested as an immune adjuvant for an antigen, influenza hemagglutinin (HA). The polymersomes were prepared according to a solvent removal method and loaded with HA antigensvia adsorption. The immunogenicity of the resulting hybrid assemblies was tested in vivo, resulting in an improvement of the immune response for the influenza antigen co-administered with the polymersomes.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
Recommended Compounds
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trans,trans-4-n-Propyl-4-[4-(trifluoromethoxy)phenyl]bicyclohexyl
CAS Number:
133937-72-1
Molecular Formula:
C22H31F3O
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