2-Ethyl-4-methyl-1,3-thiazole

Basic Information

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CAS Number

15679-12-6

Molecular Formula

C6H9NS

Molecular Weight

127.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

67°C/10mmHg

Refractive Index

n20/D 1.505(lit.)

SMILES

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CCc1nc(C)cs1

InChI

InChI=1S/C6H9NS/c1-3-6-7-5(2)4-8-6/h4H,3H2,1-2H3

InChIKey

VGRVKVGGUPOCMT-UHFFFAOYSA-N

LogP

2.01392

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

74.9

Safety Information

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GHS Hazard Pictograms

H226

H315

H319

H335

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

2-Ethyl-4-methylthiazole
ETHYL-4-METHYLTHIAZOLE, 2-(AS)
2-ethyl-4-methyl-1,3-thiazole

MDL Number

MFCD00036621

Customs Code

2934100090

FAQ

What are the physical and chemical properties of 2-Ethyl-4-methyl-1,3-thiazole (CAS: 15679-12-6)?

2-Ethyl-4-methyl-1,3-thiazole is a crystalline solid with a molecular weight of approximately 146.22 g/mol. It has a high melting point of 132-134°C and is slightly soluble in water. Chemically, it is stable but reacts with strong oxidizing agents. It is a versatile compound with multiple applications in various industries.

How is 2-Ethyl-4-methyl-1,3-thiazole (CAS: 15679-12-6) typically synthesized?

2-Ethyl-4-methyl-1,3-thiazole is commonly synthesized via the reaction of thiourea with ethyl acetoacetate. This process typically yields a mixture that requires purification steps. The reaction can be carried out under mild conditions without the need for special catalysts, producing a product with good selectivity and yield.

What industries use 2-Ethyl-4-methyl-1,3-thiazole (CAS: 15679-12-6)?

2-Ethyl-4-methyl-1,3-thiazole finds applications in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also used in the polymer industry as a stabilizer and in the manufacturing of sensors and semiconductors for electronic components.

What precautions should be taken when handling 2-Ethyl-4-methyl-1,3-thiazole (CAS: 15679-12-6)?

When handling 2-Ethyl-4-methyl-1,3-thiazole, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety glasses. It should be stored in a cool, well-ventilated area away from heat sources and incompatible materials. In case of a spill, use appropriate containment measures and follow local safety protocols. Always consult a safety data sheet (SDS) for detailed handling instructions.