Asymmetric catalysis with bifunctional cinchona alkaloid-based urea and thiourea organocatalysts

Literature Information

Publication Date 2008-02-21
DOI 10.1039/B719249E
Impact Factor 6.222
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Abstract

Cinchona alkaloid derivatives modified to include a (thio)urea component have emerged in the last three years as readily accessible, robust and tunable bifunctional organocatalysts for a range of synthetically useful transformations. The origins of these catalysts and the major developments in their application in enantioselective synthesis are reviewed.

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