Highly stereoselective synthesis of (−)-monatin, a high-intensity sweetener, using chelation-controlled nitrone cycloaddition

Literature Information

Publication Date 2003-09-24
DOI 10.1039/B306791M
Impact Factor 6.222
Authors

Osamu Tamura, Tomoya Shiro, Atsushi Toyao, Hiroyuki Ishibashi


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Abstract

Synthesis of (−)-monatin was achieved by chelation-controlled cycloaddition of nitrone 2 with allyl alcohol 3a in the presence of MgBr2·OEt2.

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Chemical Communications

Chemical Communications
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