Highly stereoselective synthesis of (−)-monatin, a high-intensity sweetener, using chelation-controlled nitrone cycloaddition
Literature Information
Osamu Tamura, Tomoya Shiro, Atsushi Toyao, Hiroyuki Ishibashi
Synthesis of (−)-monatin was achieved by chelation-controlled cycloaddition of nitrone 2 with allyl alcohol 3a in the presence of MgBr2·OEt2.
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