First example of electrophile induced Baylis–Hillman reaction: a novel facile one-pot synthesis of indolizine derivatives
Literature Information
Deevi Basavaiah, Anumolu Jaganmohan Rao
Treatment of pyridine-2-carboxaldehyde with activated alkenes such as alkyl vinyl ketones and cyclic enones in the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) provides a novel facile one-pot synthesis of indolizine derivatives, thus for the first time describing an electrophile induced Baylis–Hillman reaction.
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