Design and synthesis of potent N1-substituted indolemelatonin receptor agonists

Literature Information

Publication Date 2003-01-14
DOI 10.1039/B210731G
Impact Factor 6.222
Authors

Andrew Tsotinis, Andreas Eleutheriades, Katherine Hough, David Sugden


View Original

Abstract

The design and expeditious synthesis of two new indole analogs with up to 5-fold potency of that of melatonin is described.

Related Literature

Front cover

2021-06-16 Cover

DOI: 10.1039/D1CP90121D

Room-temperature diffusion of metal clusters on graphene

Mohammad Zarshenas, Victor Gervilla, Davide G. Sangiovanni, Kostas Sarakinos

2021-05-24 Paper

DOI: 10.1039/D1CP00522G

Bayesian phase difference estimation: a general quantum algorithm for the direct calculation of energy gaps

Chikako Sakai, Kazuo Toyota, Kazunobu Sato, Daisuke Shiomi

2021-09-02 Paper

DOI: 10.1039/D1CP03156B

Self-assembled, optically-active {naphthalene diimide}U{cucurbit[8]uril} ensembles in an aqueous environment

Heather F. Higginbotham, Subashani Maniam, Tina Hsia, Lyle Isaacs, Steven J. Langford, Toby D. M. Bell

2021-06-02 Communication

DOI: 10.1039/D1CP00659B

Contents list

2021-06-16 Front/Back Matter

DOI: 10.1039/D1CP90122B

Surface electronic states mediate concerted electron and proton transfer at metal nanoscale interfaces for catalytic hydride reduction of –NO2 to –NH2

Bing-Qian Shan, Jia-Feng Zhou, Meng Ding, Xiao-Dan Hu

2021-05-25 Communication

DOI: 10.1039/D1CP01792F

Prediction of the standard potentials for one-electron oxidation of N,N,N′,N′ tetrasubstituted p-phenylenediamines by calculation

Cecilie L. Andersen, Evanildo G. Lacerda, Jr, Jørn B. Christensen, Stephan P. A. Sauer, Ole Hammerich

2021-09-02 Paper

DOI: 10.1039/D1CP02315B

Exceptionally high saturation magnetisation in Eu-doped magnetite stabilised by spin–orbit interaction

M. Hussein N. Assadi, José Julio Gutiérrez Moreno, Dorian A. H. Hanaor, Hiroshi Katayama-Yoshida

2021-09-02 Paper

DOI: 10.1039/D1CP02164H

You might also like

Compound Q&A

What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?

N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...

52818-63-0N-(4-Methoxybenzyl)-...
Compound Q&A

What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?

When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...

1050507-06-6Ethyl 4-(2-chlorophe...
Compound Q&A

What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?

Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...

628-39-7Diethyldiselane
Compound Q&A

What is the market or research trend for oxocopper (CAS: 12053-18-8)?

The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...

12053-18-8oxocopper; oxo-(oxoc...
Compound Q&A

What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?

The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...

1268519-54-55-{[(2-Methyl-2-prop...
Compound Q&A

What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?

2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...

35981-63-62-(1-Pyrrolidinyl)-4...
Compound Q&A

What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?

2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...

91556-75-12-(3-Pyridinyl)-1-az...
Compound Q&A

How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?

(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...

129704-91-2(S)-Alpha-allyl-prol...
Compound Q&A

What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?

3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...

4857-42-53-Methyl-1,2-oxazole...
Compound Q&A

How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?

Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...

1281816-04-3Lys-SMCC-DM1

Source Journal

Chemical Communications

Chemical Communications
CiteScore: 8.6
Self-citation Rate: 4.7%
Articles per Year: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.