(5E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one | CAS No. 99972-65-3
(5E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one
Basic Information
CAS Number
99972-65-3
Molecular Formula
C11H9NO3S2
Molecular Weight
267.33 g/mol
AD
Chemical Classification
Basic Physical Properties
Safety Information
View Safety InformationHazard Class
Class IRRITANT
Class IRRITANT
Synonyms & References
English
- (5E)-5-[(2-hydroxy-3-methoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one
- (5E)-5-(2-hydroxy-3-methoxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one
- (5E)-5-[(2-hydroxy-3-methoxyphenyl)methylidene]-2-sulfanyl-4,5-dihydro-1,3-thiazol-4-one
- (5E)-5-(2-hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one
- AKOS000409114
- 5-[(2-HYDROXY-3-METHOXYPHENYL)METHYLENE]-2-THIOXO-1,3-THIAZOLAN-4-ONE
- (E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-mercaptothiazol-4(5H)-one
- MFCD04969025
- 99972-65-3
- SCHEMBL8193222
- AKOS000307425
- (5E)-5-(2-HYDROXY-3-METHOXYBENZYLIDENE)-2-MERCAPTO-1,3-THIAZOL-4(5H)-ONE
- 5-((Z)-(2-hydroxy-3-methoxybenzylidene))-2-thioxo-4-thiazolidinone
MDL Number
MFCD04969025
Customs Code
2934999090
FAQ
What are the physical and chemical properties of (5E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one (CAS: 99972-65-3)?
(5E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one is a crystalline compound with a high molecular weight, showing good solubility in organic solvents. It exhibits excellent reactivity towards nucleophiles and can form stable adducts. This compound is known for its high thermal stability and low volatility. It is typically used in the preparation of bioactive molecules and other organic compounds.
How is (5E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one (CAS: 99972-65-3) typically synthesized?
(5E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one is synthesized via a condensation reaction between a thiosemicarbazide and a substituted benzaldehyde, catalyzed by a Lewis acid. The reaction yields high purity and good selectivity, with a yield of up to 85%. This method provides a practical and efficient route to the synthesis of this important chemical intermediate.
What industries use (5E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one (CAS: 99972-65-3)?
(5E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one finds application in the pharmaceutical industry for the synthesis of bioactive compounds, in polymer science for the development of new materials, and in the production of sensors and semiconductors. This compound is valued for its unique chemical properties and its ability to form stable adducts with various functional groups.
What precautions should be taken when handling (5E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one (CAS: 99972-65-3)?
When handling (5E)-5-(2-Hydroxy-3-methoxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate procedures, and the substance is to be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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