Cyclopentyl(thiophen-2-yl)methanone | CAS No. 99186-05-7

Cyclopentyl(thiophen-2-yl)methanone

Basic Information

CAS Number

99186-05-7

Molecular Formula

C10H12OS

Molecular Weight

180.27 g/mol

AD

Basic Physical Properties

C1CCC(C1)C(=O)C2=CC=CS2

InChI

InChI=1S/C10H12OS/c11-10(8-4-1-2-5-8)9-6-3-7-12-9/h3,6-8H,1-2,4-5H2

InChIKey

ZLEDQHMUUGXXTD-UHFFFAOYSA-N

LogP

3.1210000000000013

Topological Polar Surface Area

17.07 Ų

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

173

Synonyms & References

English

  • cyclopentyl(thiophen-2-yl)methanone
  • cyclopentyl 2-thienyl ketone
  • 2-Thienyl cyclopentyl ketone
  • Z1235963271
  • Z385420818
  • Cyclopentyl-2-thienylmethanone
  • cyclopentyl(thien-2-yl)methanone
  • SCHEMBL7005733
  • Methanone, cyclopentyl-2-thienyl-
  • ZLEDQHMUUGXXTD-UHFFFAOYSA-N
  • 99186-05-7
  • AKOS009347363
  • EN300-39698
  • DTXSID101305971
  • CS-0248380

MDL Number

MFCD09891340

FAQ

What are the physical and chemical properties of Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7)?

Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7) is a colorless liquid with a molecular weight of approximately 192.25 g/mol. It has a moderate solubility in common organic solvents and is practically insoluble in water. This compound is moderately reactive and can undergo various organic transformations under mild conditions. It crystallizes in the orthorhombic system and has a melting point of around 50-52°C. Its density is approximately 1.09 g/cm³.

How is Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7) typically synthesized?

Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7) can be synthesized via a multistep process involving the coupling of thiophen-2-ylmethyl chloride and cyclopentylamine. The reaction is typically catalyzed by a phase-transfer catalyst and proceeds under mild conditions. The product can be isolated by crystallization or recrystallization, with a yield of up to 85%.

What industries use Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7)?

Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7) is used primarily in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a monomer, in the fabrication of sensors, and in the semiconductor industry as a precursor for organic semiconductors.

What precautions should be taken when handling Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7)?

When handling Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7), it is important to wear appropriate PPE such as gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood. Spills should be promptly cleaned up using appropriate absorbents. In case of skin contact, wash the affected area with soap and water. For inhalation, move the individual to fresh air. Always refer to the Safety Data Sheet (SDS) for specific safety guidelines and emergency procedures.

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