Cyclopentyl(thiophen-2-yl)methanone(CAS: 99186-05-7)

Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7) is a colorless liquid with a molecular weight of approximately 192.25 g/mol. It has a moderate solubility in common organic solvents and is practically insoluble in water. This compound is moderately reactive and can undergo various organic transformations under mild conditions. It crystallizes in the orthorhombic system and has a melting point of around 50-52°C. Its density is approximately 1.09 g/cm³.

Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7) can be synthesized via a multistep process involving the coupling of thiophen-2-ylmethyl chloride and cyclopentylamine. The reaction is typically catalyzed by a phase-transfer catalyst and proceeds under mild conditions. The product can be isolated by crystallization or recrystallization, with a yield of up to 85%.

Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7) is used primarily in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a monomer, in the fabrication of sensors, and in the semiconductor industry as a precursor for organic semiconductors.

When handling Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7), it is important to wear appropriate PPE such as gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood. Spills should be promptly cleaned up using appropriate absorbents. In case of skin contact, wash the affected area with soap and water. For inhalation, move the individual to fresh air. Always refer to the Safety Data Sheet (SDS) for specific safety guidelines and emergency procedures.