Compound Q&A

How is Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7) typically synthesized?

Answer

Cyclopentyl(thiophen-2-yl)methanone
Cyclopentyl(thiophen-2-yl)methanone (CAS: 99186-05-7) can be synthesized via a multistep process involving the coupling of thiophen-2-ylmethyl chloride and cyclopentylamine. The reaction is typically catalyzed by a phase-transfer catalyst and proceeds under mild conditions. The product can be isolated by crystallization or recrystallization, with a yield of up to 85%.

About

CAS No 99186-05-7
English Name Cyclopentyl(thiophen-2-yl)methanone
Molecular Formula C10H12OS
Molecular Weight 180.27 g/mol
SMILES C1CCC(C1)C(=O)C2=CC=CS2
InChIKey ZLEDQHMUUGXXTD-UHFFFAOYSA-N
Last Updated: 2026-04-01 14:15

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