Norfloxacin lactate

Basic Information

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CAS Number

97867-34-0

Molecular Formula

C19H24FN3O6

Molecular Weight

409.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

SMILES

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CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O.CC(C(=O)O)O

InChI

InChI=1S/C16H18FN3O3.C3H6O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20;1-2(4)3(5)6/h7-9,18H,2-6H2,1H3,(H,22,23);2,4H,1H3,(H,5,6)

InChIKey

AYEXIHJJZPTXSS-UHFFFAOYSA-N

LogP

0.7201000000000004

Topological Polar Surface Area

132.10000000000002 Å²

Hydrogen Bond Donor/Acceptor

4 / 9

Complexity

578

Synonyms & References

English

NORFLOXACIN LACTATE
[ "" ]
3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, mono(2-hydroxypropanoate) (9CI)
Propanoic acid, 2-hydroxy-, compd. with 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid (1:1) (9CI)
Norfloxacin lactate
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;2-hydroxypropanoic acid
97867-34-0
UNII-GU3OE7CPD0
GU3OE7CPD0
MK-0366
3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, mono(2-hydroxypropanoate)
Norfloxacin lactate [WHO-DD]

FAQ

What are the physical and chemical properties of Norfloxacin lactate (CAS: 97867-34-0)?

Norfloxacin lactate is a crystalline compound with a molecular weight of approximately 596.58 g/mol. It has a solubility of about 1.22 g/100 mL in water. Chemically, it is moderately reactive, particularly towards acidic and basic conditions. It is stable under normal storage conditions but should be protected from moisture and light.

How is Norfloxacin lactate (CAS: 97867-34-0) typically synthesized?

Norfloxacin lactate is synthesized through a multi-step process involving acylation, ring formation, and lactonization. The key steps include the use of 1-(4-fluorophenyl)-3-(piperazin-1-yl)-2-propanol as the starting material, followed by acylation with 3-nitrobenzoyl chloride. This process yields Norfloxacin, which is then converted to its lactate salt using lactic acid as the reagent.

What industries use Norfloxacin lactate (CAS: 97867-34-0)?

Norfloxacin lactate is primarily used in the pharmaceutical industry for the production of antibiotics. It is also used in research for its antimicrobial properties. This compound has potential applications in developing new drugs and in the field of antimicrobial resistance research.

What precautions should be taken when handling Norfloxacin lactate (CAS: 97867-34-0)?

When handling Norfloxacin lactate, it is essential to wear appropriate personal protective equipment, including gloves and safety glasses. It should be stored in a cool, dry place away from direct sunlight and moisture. In case of a spill, handle it with care, using appropriate containment and clean-up procedures as outlined in the Safety Data Sheet (SDS).