Azido-PEG4-Amine

Basic Information

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CAS Number

951671-92-4

Molecular Formula

C10H22N4O4

Molecular Weight

262.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

Solid

Melting Point

No data available

Boiling Point

No data available

Density

1.10g/mL

Flash Point

No data available

Refractive Index

1.4670 to 1.4710

Vapor Pressure

No data available

SMILES

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C(COCCOCCOCCOCCN=[N+]=[N-])N

InChI

InChI=1S/C10H22N4O4/c11-1-3-15-5-7-17-9-10-18-8-6-16-4-2-13-14-12/h1-11H2

InChIKey

ZMBGKXBIVYXREN-UHFFFAOYSA-N

LogP

0.47486

Complexity

212

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

O-(2-Aminoethyl)-O’-(2-azidoethyl)triethylene Glycol
Azido-PEG4-Amine
14-AZIDO-3,6,9,12-TETRAOXATETRADECAN-1-YLAMINE
2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
N3-PEG4-CH2CH2NH2
N3-PEG5-NH2
O-(2-AMinoethyl)-O'-(2-azidoethyl)triethylene Glycol
14-Azido-3,6,9,12-tetraoxatetradecan-1-amine
1-Amino-14-azido-3,6,9,12-tetraoxatetradecane
Amino-PEG4-Azide
14-Amino-3,6,9,12-tetraoxatetradecanyl Azide
Azido-PEG4-amine,N3-PEG4-NH2
N3-PEG4-C2-NH2
SY234209
2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethylamine
2-
14-Azido-3,6,9,12-tetraoxatetradecan-1-amine (ACI)
2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
C70098
Azido-PEG4-NH2
AKOS030213723
HY-128834
951671-92-4
Amino-PEG5-azide
BP-21615
LCZC2302
AS-3276
DTXSID60746997
A3004
2-(2-{2-[2-(2-Azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethylamine
MFCD20134134

MDL Number

MFCD20134134

FAQ

What are the physical and chemical properties of Azido-PEG4-Amine (CAS: 951671-92-4)?

Azido-PEG4-Amine (CAS: 951671-92-4) is a polyethylene glycol derivative with a molecular weight of approximately 450 Da. It is a white or off-white solid with a crystalline form. The compound has a high solubility in common organic solvents such as DMSO and DMF. It is reactive towards amine groups, enabling its use in conjugation reactions. The compound can be used in polymer synthesis and bioconjugation applications.

How is Azido-PEG4-Amine (CAS: 951671-92-4) typically synthesized?

Azido-PEG4-Amine (CAS: 951671-92-4) is typically synthesized by condensation of azide and amine functionalities on a polyethylene glycol backbone. The reaction involves the coupling of a primary amine with an azide group under mild conditions, often in the presence of a coupling agent like EDC (1-ethyl-3-(3-dimethylaminopropyl) carbodiimide) and HOBt (1-hydroxybenzotriazole). The yield is around 80-90% under optimal conditions.

What industries use Azido-PEG4-Amine (CAS: 951671-92-4)?

Azido-PEG4-Amine (CAS: 951671-92-4) is widely used in the pharmaceutical industry for drug delivery systems and biomolecule conjugation. It is also utilized in polymer chemistry for the synthesis of functional polymers. The compound finds applications in the development of biosensors and semiconductor materials for electronic devices.

What precautions should be taken when handling Azido-PEG4-Amine (CAS: 951671-92-4)?

When handling Azido-PEG4-Amine (CAS: 951671-92-4), appropriate personal protective equipment (PPE) is essential, including gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using appropriate absorbents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.