Compound Q&A

How is Azido-PEG4-Amine (CAS: 951671-92-4) typically synthesized?

Answer

Azido-PEG4-Amine
Azido-PEG4-Amine (CAS: 951671-92-4) is typically synthesized by condensation of azide and amine functionalities on a polyethylene glycol backbone. The reaction involves the coupling of a primary amine with an azide group under mild conditions, often in the presence of a coupling agent like EDC (1-ethyl-3-(3-dimethylaminopropyl) carbodiimide) and HOBt (1-hydroxybenzotriazole). The yield is around 80-90% under optimal conditions.

About

English Name Azido-PEG4-Amine
Molecular Formula C10H22N4O4
Molecular Weight 262.31 g/mol
SMILES C(COCCOCCOCCOCCN=[N+]=[N-])N
InChIKey ZMBGKXBIVYXREN-UHFFFAOYSA-N
Last Updated: 2025-10-13 17:50

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