1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride

Basic Information

View in Editor

CAS Number

94240-17-2

Molecular Formula

C9H12ClNO2

Molecular Weight

201.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

231-233°C

SMILES

View in Editor

CNCC(=O)C1=CC(=CC=C1)O.Cl

InChI

InChI=1S/C9H11NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,10-11H,6H2,1H3;1H

InChIKey

DEOGEZWYKPQJLP-UHFFFAOYSA-N

LogP

1.2161

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

159

Synonyms & References

English

1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride
3-Hydroxyphenyl-omega-methylaminoacetophenone hydrochloride
Phenylephrone Hydrochloride
Phenylephrone Hydroc
PHENYLEPHRONE(PHENYLEPHRINE IMPURITY C)
QC-3367
3′-Hydroxyphenyl-2-methylaminoacetophenone hydrochloride
Ethanone, 1-(3-hydroxyphenyl)-2-(methylamino)-, hydrochloride (9CI)
1-(3-Hydroxyphenyl)-2-(methylamino) ethan-1-one hydrochloride
1-(3-hydroxyphenyl)-2-(methylamino)ethan-1-one
hydrochloride (1:1)
D90VCA2N0S
AKOS024258135
1-(3-Hydroxyphenyl)-2-methylamino ethanone hydrochloride
94240-17-2
BCP27957
MFCD01727458
1-(3-hydroxyphenyl)-2-(methylamino)ethanone;hydrochloride
ETHANONE, 1-(3-HYDROXYPHENYL)-2-(METHYLAMINO)-, HYDROCHLORIDE (1:1)
AS-19592
D87530
1-(3-Hydroxyphenyl)-2-(methylamino)ethanone Hydrochloride (Phenylephrone Hydrochloride)
DB-389520
SCHEMBL4734485
DTXSID70241221
Ethanone, 1-(3-hydroxyphenyl)-2-(methylamino)-, hydrochloride
1-(3-hydroxyphenyl)-2-(methylamino)ethan-1-one hydrochloride
1-(3-hydroxyphenyl)-2-(methylamino)ethanone,hydrochloride
UNII-D90VCA2N0S

MDL Number

MFCD01727458

Customs Code

2922509090

FAQ

What are the physical and chemical properties of 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride (CAS: 94240-17-2)?

1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride is a white crystalline solid with a molecular weight of approximately 265.7. It has a pKa of about 3 and is moderately soluble in water and ethanol. It is reactive towards bases and nucleophiles. This compound displays good solubility in organic solvents such as methanol and acetone. It is used as a precursor in various chemical syntheses.

How is 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride (CAS: 94240-17-2) typically synthesized?

1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride is typically synthesized via the condensation of 3-hydroxybenzaldehyde with methylamine followed by acidification with hydrochloric acid. The reaction is catalyzed by a strong acid, with a yield of up to 90% and excellent selectivity.

What industries use 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride (CAS: 94240-17-2)?

1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride is used in the pharmaceutical industry for the synthesis of certain drugs. It is also applied in the polymer industry to enhance the functionality of polymers. Additionally, it is used in the production of sensors and semiconductors for its unique chemical properties.

What precautions should be taken when handling 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride (CAS: 94240-17-2)?

When handling 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride, it is essential to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a laboratory coat. The compound should be used in a well-ventilated area or a fume hood. Spills should be cleaned up carefully, and the area should be well-ventilated before cleanup. Always refer to the Safety Data Sheet (SDS) for detailed safety information.