Compound Q&A

How is 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride (CAS: 94240-17-2) typically synthesized?

Answer

1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride
1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride is typically synthesized via the condensation of 3-hydroxybenzaldehyde with methylamine followed by acidification with hydrochloric acid. The reaction is catalyzed by a strong acid, with a yield of up to 90% and excellent selectivity.

About

CAS No 94240-17-2
English Name 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride
Molecular Formula C9H12ClNO2
Molecular Weight 201.653 g/mol
SMILES CNCC(=O)C1=CC(=CC=C1)O.Cl
InChIKey DEOGEZWYKPQJLP-UHFFFAOYSA-N
Last Updated: 2025-10-10 13:51

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