p-(Trifluoromethoxy)benzenesulphonyl chloride

Basic Information

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CAS Number

94108-56-2

Molecular Formula

C7H4ClF3O3S

Molecular Weight

260.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

120-122 ºC (15 mmHg)

Density

1.536 g/mL at 25 °C

Refractive Index

n20/D 1.479(lit.)

Vapor Pressure

0.23 psi ( 20 °C)

SMILES

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C1=CC(=CC=C1OC(F)(F)F)S(=O)(=O)Cl

InChI

InChI=1S/C7H4ClF3O3S/c8-15(12,13)6-3-1-5(2-4-6)14-7(9,10)11/h1-4H

InChIKey

UHCDBMIOLNKDHG-UHFFFAOYSA-N

LogP

2.5127000000000006

Topological Polar Surface Area

43.370000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

300

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

4-(Trifluoromethoxy)benzene-1-sulfonyl chloride
4-(Trifluoromethoxy)benzenesulphonyl chloride
4-(Trifluoromethoxy)benzenesulfonyl chloride
4-Trifluoromethoxybenzenesulphonyl Chloride
p-(Trifluoromethoxy)benzenesulfonyl Chloride
4-trifluoromethoxy-benzenesulfonylchloride
4-trifluoromethoxyphenyl-sulfonylchloride
4-trifluoromethyloxyphenylsulfony chloride
4-(Trifluoromethoxy)benzenesulfonyl chloride (ACI)
4-(Trifluoromethoxy)benzenesulfonic acid chloride
4-(Trifluoromethoxy)phenylsulfonyl chloride
p-(Trifluoromethoxy)benzenesulfonyl chloride
4-trifluoromethoxybenzenesulfonylchloride
4-trifluoromethoxy-benzenesulfonyl chloride
4-trifluoromethoxybenzenesulphonyl chloride
BBL027983
Benzenesulfonyl chloride, 4-(trifluoromethoxy)-
4-(trifluoromethoxy)benzene-1-sulfonyl chloride
4-trifluoromethoxyphenyl sulfonyl chloride
4-(trifluoromethoxy)benzene-sulfonyl chloride
F16177
4-(Trifluoromethoxy)benzene sulfonyl chloride
4-(trifluoromethoxy)-benzenesulfonyl chloride
EN300-09800
4-trifluoromethoxybenzenesulfonyl chloride
T2146
NS00064151
F2167-0063
4-(trifluoromethyloxy)benzenesulfonyl chloride
DTXCID30163071
4-(Trifluoromethoxy)benzenesulfonyl chloride #

MDL Number

MFCD00042408

Customs Code

2909309090

FAQ

What are the physical and chemical properties of p-(Trifluoromethoxy)benzenesulphonyl chloride (CAS: 94108-56-2)?

p-(Trifluoromethoxy)benzenesulphonyl chloride is a white crystalline solid with a molecular weight of approximately 310.11 g/mol. It is slightly soluble in water and has good solubility in organic solvents such as dichloromethane and acetonitrile. Chemically, it is a reactive compound, prone to nucleophilic substitution and electrophilic aromatic substitution reactions.

How is p-(Trifluoromethoxy)benzenesulphonyl chloride (CAS: 94108-56-2) typically synthesized?

p-(Trifluoromethoxy)benzenesulphonyl chloride can be synthesized by the reaction of p-(trifluoromethoxy)benzene with thionyl chloride. This process typically involves the use of a catalyst to improve yield and selectivity. The reaction is carried out under anhydrous conditions to prevent hydrolysis and typically requires a fume hood for safety.

What industries use p-(Trifluoromethoxy)benzenesulphonyl chloride (CAS: 94108-56-2)?

p-(Trifluoromethoxy)benzenesulphonyl chloride is primarily used in the pharmaceutical industry for the synthesis of drug intermediates and in the polymer industry for the production of specialized polymers. It is also utilized in the sensors and semiconductor industries for the development of advanced materials.

What precautions should be taken when handling p-(Trifluoromethoxy)benzenesulphonyl chloride (CAS: 94108-56-2)?

Proper personal protective equipment (PPE) is essential when handling p-(Trifluoromethoxy)benzenesulphonyl chloride. This includes gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area, preferably in a fume hood. Spills should be cleaned up carefully following standard safety procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.