2'-Deoxyguanosine-5'-triphosphate trisodium salt

Basic Information

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CAS Number

93919-41-6

Molecular Formula

C10H13N5Na3O13P3

Molecular Weight

573.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Insecticides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Solid

Melting Point

>0°C

SMILES

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C1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O.[Na+].[Na+].[Na+]

InChI

InChI=1S/C10H16N5O13P3.3Na/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17);;;/q;3*+1/p-3/t4-,5+,6+;;;/m0.../s1

InChIKey

IWGGLKOTEOCWQP-BIHLCPNHSA-K

LogP

0.58930

Complexity

895

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H360 May damage fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

2'-deoxyguanosine 5'-triphosphate disodium salt
2-Deoxyguanosine 5-triphosphoric acid trisodium salt (dGTP)
2′-Deoxyguanosine 5′-triphosphate trisodium salt
2'-Deoxyguanosine 5'-triphosphate trisodium salt
2'-Deoxyguanosine-5'-triphosphate trisodium salt
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE TRISODIUM SALT, DGTP
dGTP, Na3, 2H2O
2′-Deoxyguanosine 5′-triphosphate solution
dGTP-Na3
2′-deoxy-guanosine-5′-triphosphate
deoxy-guanosine-5′-triphosphate, 2′-
2'-Deoxyguanosine 5'-(tetrahydrogen triphosphate) trisodium salt
dGTP.Na3
dGTP
Deoxyguanosine triphosphate
deoxy-GTP
Deoxyguanosine 5'-triphosphate
2'-Deoxyguanosine 5'-triphosphate
5'-DGTP
2'-Deoxyguanosine 5'-(tetrahydrogen triphosphate)
2'-deoxyguanosine-5'-triphosphate
Guanosine 2'-deoxy-, 5'-triphosphate
Guanosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate)
2'-Deoxyguanosine triphosphate
8C2O37Y44Q
Guanosine 5'-(tetrahydrogen triphosphate), 2'-deoxy- (9CI)
Guanosine 5'-(tetrahydrogen triphosphate),
Guanosine 5′-(tetrahydrogen triphosphate), 2′-deoxy-, trisodium salt (9CI)
Sodium 2′-deoxyguanosine 5′-(tetrahydrogen triphosphate) (3:1) (ACI)
Deoxyguanosine triphosphate trisodium salt
dgtp-na3；Disodium 5'-dGMP

MDL Number

MFCD00080337

FAQ

What are the physical and chemical properties of 2'-Deoxyguanosine-5'-triphosphate trisodium salt (CAS: 93919-41-6)?

2'-Deoxyguanosine-5'-triphosphate trisodium salt is a stable crystalline compound with a molecular weight of approximately 655.16 g/mol. It is highly soluble in water and moderately soluble in ethanol. This compound is known for its low reactivity under standard laboratory conditions, making it suitable for storage and handling. The compound exhibits good stability in dry form but requires careful handling in aqueous solutions to prevent degradation.

How is 2'-Deoxyguanosine-5'-triphosphate trisodium salt (CAS: 93919-41-6) typically synthesized?

2'-Deoxyguanosine-5'-triphosphate trisodium salt is typically synthesized through a multistep process involving the conversion of deoxyguanosine to its triphosphate form and subsequent sodium salt formation. Commonly, this involves the use of adenylate kinase to convert deoxyguanosine-5'-monophosphate to deoxyguanosine-5'-diphosphate and then triphosphate. The sodium salt is then formed by the addition of sodium ions, often using a base like sodium carbonate or bicarbonate. The exact conditions, such as temperature and pH, are optimized for high yield and selectivity.

What industries use 2'-Deoxyguanosine-5'-triphosphate trisodium salt (CAS: 93919-41-6)?

2'-Deoxyguanosine-5'-triphosphate trisodium salt finds applications in the pharmaceutical industry, particularly in the development of nucleoside-based drugs and therapeutic agents. It is also used in the polymer industry for the synthesis of nucleic acid-based polymers and in the sensor industry for the development of nucleic acid biosensors. Additionally, this compound may be utilized in semiconductor manufacturing processes as part of nucleic acid-based materials.

What precautions should be taken when handling 2'-Deoxyguanosine-5'-triphosphate trisodium salt (CAS: 93919-41-6)?

When handling 2'-Deoxyguanosine-5'-triphosphate trisodium salt, it is important to use personal protective equipment (PPE) such as gloves and safety glasses. Work in a well-ventilated area or a fume hood to minimize exposure to airborne particles. Spills should be handled carefully using appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for specific safety information and procedures. Store the compound in a cool, dry place away from direct sunlight and heat sources.