How is 2'-Deoxyguanosine-5'-triphosphate trisodium salt (CAS: 93919-41-6) typically synthesized?

2'-Deoxyguanosine-5'-triphosphate trisodium salt is typically synthesized through a multistep process involving the conversion of deoxyguanosine to its triphosphate form and subsequent sodium salt formation. Commonly, this involves the use of adenylate kinase to convert deoxyguanosine-5'-monophosphate to deoxyguanosine-5'-diphosphate and then triphosphate. The sodium salt is then formed by the addition of sodium ions, often using a base like sodium carbonate or bicarbonate. The exact conditions, such as temperature and pH, are optimized for high yield and selectivity.