2'-Deoxyguanosine-5'-triphosphate trisodium salt(CAS: 93919-41-6)

2'-Deoxyguanosine-5'-triphosphate trisodium salt is a stable crystalline compound with a molecular weight of approximately 655.16 g/mol. It is highly soluble in water and moderately soluble in ethanol. This compound is known for its low reactivity under standard laboratory conditions, making it suitable for storage and handling. The compound exhibits good stability in dry form but requires careful handling in aqueous solutions to prevent degradation.

2'-Deoxyguanosine-5'-triphosphate trisodium salt is typically synthesized through a multistep process involving the conversion of deoxyguanosine to its triphosphate form and subsequent sodium salt formation. Commonly, this involves the use of adenylate kinase to convert deoxyguanosine-5'-monophosphate to deoxyguanosine-5'-diphosphate and then triphosphate. The sodium salt is then formed by the addition of sodium ions, often using a base like sodium carbonate or bicarbonate. The exact conditions, such as temperature and pH, are optimized for high yield and selectivity.

2'-Deoxyguanosine-5'-triphosphate trisodium salt finds applications in the pharmaceutical industry, particularly in the development of nucleoside-based drugs and therapeutic agents. It is also used in the polymer industry for the synthesis of nucleic acid-based polymers and in the sensor industry for the development of nucleic acid biosensors. Additionally, this compound may be utilized in semiconductor manufacturing processes as part of nucleic acid-based materials.

When handling 2'-Deoxyguanosine-5'-triphosphate trisodium salt, it is important to use personal protective equipment (PPE) such as gloves and safety glasses. Work in a well-ventilated area or a fume hood to minimize exposure to airborne particles. Spills should be handled carefully using appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for specific safety information and procedures. Store the compound in a cool, dry place away from direct sunlight and heat sources.