2,4,7-Trichloropyrido[2,3-d]pyrimidine

Basic Information

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CAS Number

938443-20-0

Molecular Formula

C7H2Cl3N3

Molecular Weight

234.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

316.4±42.0℃ at 760 mmHg

Density

1.685

Refractive Index

1.688

SMILES

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C1=CC(=NC2=C1C(=NC(=N2)Cl)Cl)Cl

InChI

InChI=1S/C7H2Cl3N3/c8-4-2-1-3-5(9)12-7(10)13-6(3)11-4/h1-2H

InChIKey

DNFDLCRLLQVUQK-UHFFFAOYSA-N

LogP

2.9849999999999994

Topological Polar Surface Area

38.67 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

192

Synonyms & References

English

2,4,7-Trichloropyrido[2,3-d]pyrimidine
Pyrido[2,3-d]pyrimidine,2,4,7-trichloro-
2,4,7-trichloro-pyrido[2,3-d]pyrimidine
zlchem 38
PubChem20630
C7H2Cl3N3
QC-8
ZLB0025
DNFDLCRLLQVUQK-UHFFFAOYSA-N
RW3233
6004AC
PB20564
FCH1402532
SY011612
AM807611
ST2403652
AX8158866
AB0080808
2,4,7-Trichloropyrido[2,3-d]pyrimidine (ACI)
2,4,7-trichloropyrido[2,3-d]pyrimidine
AC-24556
2,4,7-Trichloropyrido[2,3-d]pyrimidine, AldrichCPR
A844720
938443-20-0
CS-B0238
EN300-3253335
J-507091
2,4,7-tris(chloranyl)pyrido[2,3-d]pyrimidine
PYRIDO[2,3-D]PYRIMIDINE, 2,4,7-TRICHLORO-
SCHEMBL1216985
AKOS015850445

MDL Number

MFCD11109463

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2,4,7-Trichloropyrido[2,3-d]pyrimidine (CAS: 938443-20-0)?

2,4,7-Trichloropyrido[2,3-d]pyrimidine is a solid with a crystalline form. Its molecular weight is approximately 292.02 g/mol. This compound has low water solubility but is soluble in organic solvents like ethanol and acetone. It is moderately reactive towards nucleophiles. It has a melting point of around 230-232°C and a boiling point of 405-406°C under reduced pressure.

How is 2,4,7-Trichloropyrido[2,3-d]pyrimidine (CAS: 938443-20-0) typically synthesized?

2,4,7-Trichloropyrido[2,3-d]pyrimidine is typically synthesized through the condensation of 2,4,7-trichloropyridine with an appropriate aldehyde in the presence of a suitable catalyst such as p-toluenesulfonic acid. The reaction proceeds with good yield and selectivity, and the product can be purified by recrystallization from ethanol.

What industries use 2,4,7-Trichloropyrido[2,3-d]pyrimidine (CAS: 938443-20-0)?

2,4,7-Trichloropyrido[2,3-d]pyrimidine finds applications in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the chemical industry for the production of dyes and pigments. Additionally, it has potential applications in the development of sensors and materials science.

What precautions should be taken when handling 2,4,7-Trichloropyrido[2,3-d]pyrimidine (CAS: 938443-20-0)?

When handling 2,4,7-Trichloropyrido[2,3-d]pyrimidine, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work must be conducted in a well-ventilated area or a fume hood. Spills should be handled with caution, using appropriate containment measures and materials. Always consult the Material Safety Data Sheet (MSDS/SDS) for detailed safety information and emergency procedures.