1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone

Basic Information

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CAS Number

92394-00-8

Molecular Formula

C12H17N3O

Molecular Weight

219.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CC(=O)N1CCN(CC1)C2=CC=C(C=C2)N

InChI

InChI=1S/C12H17N3O/c1-10(16)14-6-8-15(9-7-14)12-4-2-11(13)3-5-12/h2-5H,6-9,13H2,1H3

InChIKey

AFVUJJNEILZYJQ-UHFFFAOYSA-N

LogP

0.9372999999999997

Topological Polar Surface Area

49.57000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

241

Safety Information

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Hazard Statement

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Air Sensitive

Synonyms & References

English

Q27164229
SY019137
1-[4-(4-amino-phenyl)-piperazin-1-yl]ethanone
[4-(4-acetylpiperazin-1-yl)phenyl]amine
1-[4-(4-Aminophenyl)piperazino]ethanone
BB 0244747
NCGC00182616-01
1-acetyl-4-(4-aminophenyl)piperazine
AKOS000104069
4-(4-acetylpiperazino)-aniline
CHEMBL1700038
[4-(4-acetyl-1-piperazinyl)phenyl]amine
DTXSID90352984
1-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-one
FT-0604244
1-(4-(4-aminophenyl)piperazin-1-yl)ethan-1-one
SMR001317784
1-[4-(4-Amino-phenyl)-piperazin-1-yl]-ethanone
Oprea1_693361
EN300-343896
AC-26278
1-[4-(4-aminophenyl)-1-piperazinyl]Ethanone
HMS2213K16
4-Acetyl-1-(4-aminophenyl)piperazine
HMS3356E21
MLS002264484
4-(4-Acetylpiperazin-1-yl)aniline
1-Actyl-4-(4-aminophenyl)piperazine
AMY36335
4-(4-acetylpiperazin-1-yl) aniline
TimTec1_007041

MDL Number

MFCD01365904

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone (CAS: 92394-00-8)?

1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone is a crystalline compound with a molecular weight of approximately 315.37 g/mol. It has a high solubility in polar solvents such as water and methanol. Chemically, it is relatively stable but can react with strong acids or bases. It is not flammable and does not require special handling under normal conditions.

How is 1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone (CAS: 92394-00-8) typically synthesized?

This compound is typically synthesized through a multi-step process involving the formation of a piperazine derivative, followed by coupling with a phenol derivative. Commonly used reagents include N-hydroxysuccinimide and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide. The reaction yields a product with good selectivity and high yield, under mild conditions.

What industries use 1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone (CAS: 92394-00-8)?

1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It can also be applied in the polymer industry for the production of advanced materials. Additionally, it has potential applications in the development of sensors and semiconductors.

What precautions should be taken when handling 1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone (CAS: 92394-00-8)?

When handling 1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone, it is important to use personal protective equipment (PPE), including gloves and safety glasses. It should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.