Compound Q&A
How is 1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone (CAS: 92394-00-8) typically synthesized?
Answer
![1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone](https://static.chemtradehub.com/structs/923/92394-00-8-fde9.webp "1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone")
This compound is typically synthesized through a multi-step process involving the formation of a piperazine derivative, followed by coupling with a phenol derivative. Commonly used reagents include N-hydroxysuccinimide and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide. The reaction yields a product with good selectivity and high yield, under mild conditions.
About
CAS No
92394-00-8
English Name
1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone
Molecular Formula
C12H17N3O
Molecular Weight
219.29 g/mol
SMILES
CC(=O)N1CCN(CC1)C2=CC=C(C=C2)N
InChIKey
AFVUJJNEILZYJQ-UHFFFAOYSA-N
Last Updated: 2025-11-27 23:35
![1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}