1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone(CAS: 92394-00-8)

1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone is a crystalline compound with a molecular weight of approximately 315.37 g/mol. It has a high solubility in polar solvents such as water and methanol. Chemically, it is relatively stable but can react with strong acids or bases. It is not flammable and does not require special handling under normal conditions.

This compound is typically synthesized through a multi-step process involving the formation of a piperazine derivative, followed by coupling with a phenol derivative. Commonly used reagents include N-hydroxysuccinimide and 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide. The reaction yields a product with good selectivity and high yield, under mild conditions.

1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It can also be applied in the polymer industry for the production of advanced materials. Additionally, it has potential applications in the development of sensors and semiconductors.

When handling 1-[4-(4-Aminophenyl)-1-piperazinyl]ethanone, it is important to use personal protective equipment (PPE), including gloves and safety glasses. It should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.