4-[(3-Nitrophenyl)sulfonyl]morpholine

Basic Information

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CAS Number

91619-33-9

Molecular Formula

C10H12N2O5S

Molecular Weight

272.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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C1COCCN1S(=O)(=O)C2=CC=CC(=C2)[N+](=O)[O-]

InChI

InChI=1S/C10H12N2O5S/c13-12(14)9-2-1-3-10(8-9)18(15,16)11-4-6-17-7-5-11/h1-3,8H,4-7H2

InChIKey

XCYXNNGNLAIXNM-UHFFFAOYSA-N

LogP

2.15760

Complexity

394

Synonyms & References

English

CS-0206278
4-(3-NITROBENZENESULFONYL)MORPHOLINE
91619-33-9
NSC 41055
NSC41055
AB06557
4-(3-Nitro-benzenesulfonyl)-morpholine
4-[(3-Nitrophenyl)sulfonyl]morpholine #
4-(3-Nitrobenzene-1-sulfonyl)morpholine
SR-01000508672-1
BIM-0008034.P001
SMSF0014198
CBMicro_008083
NSC-41055
Z45515788
EU-0084027
4-(3-NITROPHENYLSULFONYL)MORPHOLINE
DTXSID90285208
AKOS000727595
MFCD00622715
METHYL3-(3-BROMO-4-HYDROXY-5-METHOXYPHENYL)-2-CYANOACRYLATE
SCHEMBL4982309
LS-07273
CB10627
4-((3-Nitrophenyl)sulfonyl)morpholine
FT-0728218
4-(3-nitrophenyl)sulfonylmorpholine
SR-01000508672
4-(3-Nitrophenylsulfonyl)morpholine
4-[(3-nitrophenyl)sulfonyl]Morpholine
Morpholine,4-[(3-nitrophenyl)sulfonyl]-

MDL Number

MFCD00622715

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-[(3-Nitrophenyl)sulfonyl]morpholine (CAS: 91619-33-9)?

4-[(3-Nitrophenyl)sulfonyl]morpholine (CAS: 91619-33-9) is a crystalline solid with a molecular weight of approximately 322.15 g/mol. It has a melting point of 165-167°C and is slightly soluble in water. It is reactive towards bases and may undergo hydrolysis. This compound exhibits good solubility in common organic solvents like methanol and acetonitrile. It is used in organic synthesis due to its sulfonyl group reactivity.

How is 4-[(3-Nitrophenyl)sulfonyl]morpholine (CAS: 91619-33-9) typically synthesized?

4-[(3-Nitrophenyl)sulfonyl]morpholine (CAS: 91619-33-9) is typically synthesized via a multi-step process, starting with morpholine and 3-nitrophenylsulfonyl chloride. The reaction involves the substitution of a morpholine ring with a 3-nitrophenylsulfonyl group. The yield is generally around 80-85%, and the reaction is typically performed under anhydrous conditions to avoid hydrolysis. Anhydrous solvents like pyridine are commonly used as catalysts.

What industries use 4-[(3-Nitrophenyl)sulfonyl]morpholine (CAS: 91619-33-9)?

4-[(3-Nitrophenyl)sulfonyl]morpholine (CAS: 91619-33-9) finds applications in various industries, particularly in pharmaceuticals for synthesis of medicinal compounds. It is also utilized in the synthesis of polymers and sensors due to its functional groups. The compound's reactivity towards bases makes it suitable for use in organic synthesis protocols, contributing to advancements in materials science and chemical engineering.

What precautions should be taken when handling 4-[(3-Nitrophenyl)sulfonyl]morpholine (CAS: 91619-33-9)?

When handling 4-[(3-Nitrophenyl)sulfonyl]morpholine (CAS: 91619-33-9), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. An SDS (Safety Data Sheet) should be readily available for reference. The compound is reactive towards bases and may cause irritation, so it is crucial to avoid contact with skin and eyes.