Streptavidin | CAS No. 9013-20-1

Streptavidin

Basic Information

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CAS Number

9013-20-1

Molecular Formula

C14H17BrClNO2S

Molecular Weight

378.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Water Solubility

Gives a clear solution at 5mg/ml in 0.1M NaCl. is soluble in water at 1 mg/mL, or in phosphate buffered saline (PBS).

Solubility

H2O: 0.1 mg/mL, clear, colorless

SMILES

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C1CC[N+](=C(C2=CC(=CC=C2)Cl)SCC(=O)O)CC1.[Br-]

InChI

InChI=1S/C14H16ClNO2S.BrH/c15-12-6-4-5-11(9-12)14(19-10-13(17)18)16-7-2-1-3-8-16;/h4-6,9H,1-3,7-8,10H2;1H

InChIKey

RTWACOLFHOBGCE-UHFFFAOYSA-N

LogP

0.00000

Complexity

351

Safety Information

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Sensitiveness

对热敏感、易吸潮

Synonyms & References

English

2-[(3-chlorophenyl)-piperidin-1-ium-1-ylidenemethyl]sulanylacetic acid;bromide
FT-0700692
CID 51062757
CHEBI:201453
EX-A4899
9013-20-1
2-[(3-chlorophenyl)-piperidin-1-ium-1-ylidenemethyl]sulfanylacetic acid;bromide
Streptavidin
Polystreptavidin
Streptavidin from Streptomyces avidinii
Streptavidin and Conjugates
STREPTAVIDIN UNCONJUGATED, LYOPHILIZED
Streptavidin, TypeII
17 units
mg protein
2-[(3-Chlorophenyl)-piperidin-1-ium-1-ylidenemethyl]sulfanylacetic acid;bromide

MDL Number

MFCD00082035

FAQ

What are the physical and chemical properties of Streptavidin (CAS: 9013-20-1)?

Streptavidin (CAS: 9013-20-1) is a tetrameric protein with a molecular weight of approximately 44 kDa. It exhibits high specificity and affinity for biotin. The protein is highly soluble in water and resistant to denaturation under mild conditions. Streptavidin is known for its exceptional stability and is commonly used in various biotechnological applications due to its unique binding properties.

How is Streptavidin (CAS: 9013-20-1) typically synthesized?

Streptavidin (CAS: 9013-20-1) is produced through fermentation of the actinomycete Streptomyces avidinii. The protein is then purified from the bacterial culture medium. Common purification methods include ion exchange chromatography and affinity chromatography. The synthesis process yields a highly purified, stable protein with high biotin-binding affinity.

What industries use Streptavidin (CAS: 9013-20-1)?

Streptavidin (CAS: 9013-20-1) is widely used in the pharmaceutical industry for drug delivery and diagnostics. It is also utilized in polymer production for functionalization and stabilization. Additionally, it is employed in sensor technology for biotin detection and in semiconductor applications for surface modification and stability enhancement.

What precautions should be taken when handling Streptavidin (CAS: 9013-20-1)?

When handling Streptavidin (CAS: 9013-20-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. Work should be conducted in a fume hood to minimize inhalation risks. In case of spillage, neutralize with an appropriate agent and dispose of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.