t-Boc-N-amido-PEG9-Amine

Basic Information

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CAS Number

890091-43-7

Molecular Formula

C25H52N2O11

Molecular Weight

556.69 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Boiling Point

609.8°C at 760 mmHg

Density

1.082

Flash Point

322.6°C

Refractive Index

1.465

SMILES

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CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN

InChI

InChI=1S/C25H52N2O11/c1-25(2,3)38-24(28)27-5-7-30-9-11-32-13-15-34-17-19-36-21-23-37-22-20-35-18-16-33-14-12-31-10-8-29-6-4-26/h4-23,26H2,1-3H3,(H,27,28)

InChIKey

RTTGVFBQUXJWJG-UHFFFAOYSA-N

LogP

0.6192000000000079

Topological Polar Surface Area

147.42000000000004 Å²

Hydrogen Bond Donor/Acceptor

3 / 13

Complexity

496

Synonyms & References

English

5,8,11,14,17,20,23,26,29-Nonaoxa-2-azahentriacontanoicacid, 31-amino-, 1,1-dimethylethyl ester
O-(2-Aminoethyl)-O′-[2-(Boc-amino)ethyl]octaethylene glycol
O-(2-Aminoethyl)-O'-[2-(Boc-amino)ethyl]octaethylene glycol
t-boc-N-amido-PEG9-amine
tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}-ethoxy)ethoxy]ethoxy}ethyl)carbamic acid tert-butyl ester
O-(2-Aminoethyl)-O inverted exclamation marka-[2-(Boc-amino)ethyl]octaethylene glycol
Boc-amido-PEG9-amine
1,1-Dimethylethyl 31-amino-5,8,11,14,17,20,23,26,29-nonaoxa-2-azahentriacontanoate (ACI)
t-Boc-N-amido-PEG9-Amine
NHBoc-PEG9-amine
Boc-PEG-amine (n=9)
MFCD03453249
DTXSID10405128
SCHEMBL21113607
CS-0114311
BocNH-PEG9-CH2CH2NH2
890091-43-7
O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL
AKOS040741402
C70743
HY-140233
Boc-PEG-amine (n=8)
SY251203
WS-01853
tert-butyl (29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosyl)carbamate
DA-71621
BP-22604
Boc-N-amido-PEG9-NH2
BOC-NH-PEG9-NH2

MDL Number

MFCD03453249

FAQ

What are the physical and chemical properties of t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7)?

t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7) is a polyethylene glycol derivative with a molecular weight of approximately 700 Da. It has a crystalline form and is soluble in polar solvents like water and methanol. It is reactive towards carboxylic acids, amine coupling, and other functional groups. This compound is used in bioconjugation and drug delivery applications due to its chemical versatility and biocompatibility.

How is t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7) typically synthesized?

t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7) is synthesized through a multistep process involving the protection of a terminal amine on PEG with a Boc group, followed by amidation with an appropriate amine. Commonly used catalysts include HOBt and DCC. The final step involves deprotection of the Boc group using trifluoroacetic acid. This process yields a high purity product with good selectivity and yield.

What industries use t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7)?

t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7) is widely used in pharmaceuticals, biotechnology, and polymer science. It serves as a key functional group in bioconjugation, drug delivery systems, and as a linker in sensor and semiconductor technology. Its versatile chemical properties make it suitable for a variety of applications in these industries.

What precautions should be taken when handling t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7)?

When handling t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, and proper waste disposal procedures should be followed. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.