t-Boc-N-amido-PEG9-Amine(CAS: 890091-43-7)

t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7) is a polyethylene glycol derivative with a molecular weight of approximately 700 Da. It has a crystalline form and is soluble in polar solvents like water and methanol. It is reactive towards carboxylic acids, amine coupling, and other functional groups. This compound is used in bioconjugation and drug delivery applications due to its chemical versatility and biocompatibility.

t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7) is synthesized through a multistep process involving the protection of a terminal amine on PEG with a Boc group, followed by amidation with an appropriate amine. Commonly used catalysts include HOBt and DCC. The final step involves deprotection of the Boc group using trifluoroacetic acid. This process yields a high purity product with good selectivity and yield.

t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7) is widely used in pharmaceuticals, biotechnology, and polymer science. It serves as a key functional group in bioconjugation, drug delivery systems, and as a linker in sensor and semiconductor technology. Its versatile chemical properties make it suitable for a variety of applications in these industries.

When handling t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, and proper waste disposal procedures should be followed. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.