Compound Q&A

How is t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7) typically synthesized?

Answer

t-Boc-N-amido-PEG9-Amine
t-Boc-N-amido-PEG9-Amine (CAS: 890091-43-7) is synthesized through a multistep process involving the protection of a terminal amine on PEG with a Boc group, followed by amidation with an appropriate amine. Commonly used catalysts include HOBt and DCC. The final step involves deprotection of the Boc group using trifluoroacetic acid. This process yields a high purity product with good selectivity and yield.

About

English Name t-Boc-N-amido-PEG9-Amine
Molecular Formula C25H52N2O11
Molecular Weight 556.69 g/mol
SMILES CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
InChIKey RTTGVFBQUXJWJG-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24

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