4,6-Dichloropicolinic acid

Basic Information

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CAS Number

88912-25-8

Molecular Formula

C6H3Cl2NO2

Molecular Weight

192 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

111-112 ºC

Boiling Point

336.6℃ at 760 mmHg

Density

1.612

Flash Point

157.4°C

Refractive Index

1.605

SMILES

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C1=C(C=C(N=C1C(=O)O)Cl)Cl

InChI

InChI=1S/C6H3Cl2NO2/c7-3-1-4(6(10)11)9-5(8)2-3/h1-2H,(H,10,11)

InChIKey

AYYUSDKNXRPJBH-UHFFFAOYSA-N

LogP

2.0866

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

165

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4,6-Dichloropicolinic acid
2-Pyridinecarboxylicacid, 4,6-dichloro-
4,6-Dichloro-2-pyridinecarboxylic acid
4,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID
2-Pyridinecarboxylic acid, 4,6-dichloro-
4,6-Dichloro-pyridine-2-carboxylic acid
4,6-Dichloropicolinicacid
2-Carboxy-4,6-dichloropyridine
AYYUSDKNXRPJBH-UHFFFAOYSA-N
BBL100356
STL554150
CM14201
AB55079
2-Pyri
4,6-dichloropyridine-2-carboxylic acid
4,6-Dichloro-2-pyridinecarboxylic acid (ACI)
Picolinic acid, 4,6-dichloro- (6CI)
4,6-Dichloropyridine-2-carboxylic acid
88912-25-8
Z1198261855
DB-078254
4,6-dichloropicolinic acid
AU-004/43501647
SY057644
AKOS006283272
4 pound not6-Dichloro-pyridine-2-carboxylic acid
AC-23270
PS-4780
J-514148
EN300-101252
CS-W018783

MDL Number

MFCD09910267

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4,6-Dichloropicolinic acid (CAS: 88912-25-8)?

4,6-Dichloropicolinic acid is a white crystalline solid with a molecular weight of 214.02 g/mol. It has a low solubility in water (0.2 g/100 mL at 25°C) and is slightly soluble in organic solvents like ethanol and acetone. It is chemically reactive, particularly towards nucleophiles and reducing agents.

How is 4,6-Dichloropicolinic acid (CAS: 88912-25-8) typically synthesized?

4,6-Dichloropicolinic acid is typically synthesized via the chlorination of picolinic acid. This process involves the reaction of picolinic acid with chlorine gas in the presence of a suitable catalyst, such as ferric chloride. The reaction is carried out at a temperature of around 50-60°C, and the yield can be up to 85%.

What industries use 4,6-Dichloropicolinic acid (CAS: 88912-25-8)?

4,6-Dichloropicolinic acid is used in various industries, including pharmaceuticals for intermediates in drug synthesis, polymers for plastic additives, and sensors for detecting heavy metals. It also plays a role in the development of semiconductors and as a chelating agent in environmental science.

What precautions should be taken when handling 4,6-Dichloropicolinic acid (CAS: 88912-25-8)?

When handling 4,6-Dichloropicolinic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be handled with caution, and it is recommended to use absorbent material. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal procedures.