4,6-Dichloropicolinic acid(CAS: 88912-25-8)

4,6-Dichloropicolinic acid is a white crystalline solid with a molecular weight of 214.02 g/mol. It has a low solubility in water (0.2 g/100 mL at 25°C) and is slightly soluble in organic solvents like ethanol and acetone. It is chemically reactive, particularly towards nucleophiles and reducing agents.

4,6-Dichloropicolinic acid is typically synthesized via the chlorination of picolinic acid. This process involves the reaction of picolinic acid with chlorine gas in the presence of a suitable catalyst, such as ferric chloride. The reaction is carried out at a temperature of around 50-60°C, and the yield can be up to 85%.

4,6-Dichloropicolinic acid is used in various industries, including pharmaceuticals for intermediates in drug synthesis, polymers for plastic additives, and sensors for detecting heavy metals. It also plays a role in the development of semiconductors and as a chelating agent in environmental science.

When handling 4,6-Dichloropicolinic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be handled with caution, and it is recommended to use absorbent material. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal procedures.