Methyl 6-bromo-4-chloroquinoline-2-carboxylate

Basic Information

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CAS Number

887587-50-0

Molecular Formula

C11H7BrClNO2

Molecular Weight

300.54 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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COC(=O)C1=NC2=C(C=C(C=C2)Br)C(=C1)Cl

InChI

InChI=1S/C11H7BrClNO2/c1-16-11(15)10-5-8(13)7-4-6(12)2-3-9(7)14-10/h2-5H,1H3

InChIKey

RHNVVFWLYMUZOZ-UHFFFAOYSA-N

LogP

3.4373000000000014

Topological Polar Surface Area

39.19 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

277

Synonyms & References

English

2-Quinolinecarboxylicacid, 6-bromo-4-chloro-, methyl ester
6-Bromo-4-chloro-quinoline-2-carboxylic acid methyl ester
methyl 6-bromo-4-chloroquinoline-2-carboxylate
6-bromo-4-chloroquinolinic acid methyl ester
NE22353
methyl 4-chloro-6-bromoquinoline-2-carboxylate
6-Bromo-4-chloro-quinoline-2-carboxylic acid methy
6-bromo-4-chloroquinoline-2-carboxylic acid methyl ester
4-Chloro-6-bromoquinoline-2-carboxylic acid methyl es
methyl 6-bromo-4-chloro-quinoline-2-carboxylate
Methyl 6-bromo-4-chloro-2-quinolinecarboxylate (ACI)
6-BROMO-4-CHLORO-QUINOLINE-2-CARBOXYLIC ACID METHYL ESTER
Methyl 6-bromo-4-chloro-quinoline-2-carboxylate
SCHEMBL22396163
SB72428
2-Quinolinecarboxylicacid,6-bromo-4-chloro-,methyl ester
6-Bromo-4-chloroquinolinic acid methyl ester
Z1134173906
MFCD07783793
DTXSID80652187
CS-D1266
AS-40142
EN300-83826
SY128869
Methyl 6-bromo-4-chloroquinoline-2-carboxylate
AKOS008154266
887587-50-0

MDL Number

MFCD07783793

Customs Code

2933499090

FAQ

What are the physical and chemical properties of Methyl 6-bromo-4-chloroquinoline-2-carboxylate (CAS: 887587-50-0)?

Methyl 6-bromo-4-chloroquinoline-2-carboxylate is a crystalline compound with a molecular weight of approximately 414.03 g/mol. It is slightly soluble in water but more soluble in organic solvents like dichloromethane. It is a solid at room temperature with a melting point of around 190-195°C. This compound shows low reactivity under normal conditions but can undergo substitution reactions with appropriate nucleophiles. It has a CAS number of 887587-50-0.

How is Methyl 6-bromo-4-chloroquinoline-2-carboxylate (CAS: 887587-50-0) typically synthesized?

Methyl 6-bromo-4-chloroquinoline-2-carboxylate can be synthesized by the reaction of methyl 4-chloroquinoline-2-carboxylate with bromine in the presence of a suitable catalyst. The reaction typically involves the substitution of the chlorine atom with a bromine atom. High selectivity and moderate yields can be achieved under these conditions. The CAS number is 887587-50-0.

What industries use Methyl 6-bromo-4-chloroquinoline-2-carboxylate (CAS: 887587-50-0)?

Methyl 6-bromo-4-chloroquinoline-2-carboxylate is primarily used in the pharmaceutical and polymer industries. It serves as a precursor for the synthesis of various medicinal compounds and is also utilized in the development of organic polymers for electronic applications. The CAS number is 887587-50-0.

What precautions should be taken when handling Methyl 6-bromo-4-chloroquinoline-2-carboxylate (CAS: 887587-50-0)?

Proper handling of Methyl 6-bromo-4-chloroquinoline-2-carboxylate (CAS: 887587-50-0) requires the use of gloves, safety goggles, and appropriate personal protective equipment (PPE). It should be stored in a cool, dry place away from direct sunlight and flammable materials. Handling should be done in a well-ventilated area or a fume hood to minimize inhalation risk. In case of spills, contaminated clothing should be removed and the area should be cleaned with water and appropriate cleaning agents. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures. The CAS number is 887587-50-0.