ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate | CAS No. 885271-93-2
ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate
Basic Information
CAS Number
885271-93-2
Molecular Formula
C11H11FN2O2
Molecular Weight
222.22 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate
- (5-FLUORO-1H-INDAZOL-3-YL)-ACETIC ACID ETHYL ESTER
- ethyl (5-fluoro-1H-indazol-3-yl)acetate
- ethyl 2-(5-fluoro-2H-indazol-3-yl)acetate
- 1h-indazole-3-acetic acid,5-fluoro-,ethyl ester
- (5-Fluoro-1H-indazol-3-yl)acetic acid ethyl ester
- 4318AH
- AB28662
- BB 0255242
- J1197
- D71960
- Ethyl 5-fluoro-1H-indazole-3-acetate (ACI)
- (5-Fluoro-1H-indazol-3-yl)-acetic acid ethyl ester
- CS-16724
- AKOS015957376
- ethyl2-(5-fluoro-1H-indazol-3-yl)acetate
- 885271-93-2
- DTXSID001289500
- RLQKHYIJSNFESC-UHFFFAOYSA-N
- SCHEMBL14979247
- EN300-234988
- F2184-0209
- 5-fluoro-1H-Indazole-3-acetic acid,ethyl ester
- Ethyl 5-fluoro-1H-indazole-3-acetate
- MFCD06739128
- CS-0102743
MDL Number
MFCD06739128
FAQ
What are the physical and chemical properties of ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate (CAS: 885271-93-2)?
Ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate (CAS: 885271-93-2) is a crystalline solid with a molecular weight of approximately 241.24 g/mol. It is slightly soluble in water and more soluble in common organic solvents like ethanol and dichloromethane. The compound shows moderate reactivity due to its functional groups, particularly the acetate ester and the indazole ring. It can undergo hydrolysis and nucleophilic substitution reactions under appropriate conditions.
How is ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate (CAS: 885271-93-2) typically synthesized?
Ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate (CAS: 885271-93-2) is typically synthesized via a multistep process involving the condensation of 5-fluoro-1H-indazole with acetyl chloride followed by an esterification reaction with ethanol. Commonly used catalysts include acid catalysts like hydrochloric acid. The synthetic route provides high selectivity and good yield of the desired product.
What industries use ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate (CAS: 885271-93-2)?
Ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate (CAS: 885271-93-2) is primarily used in the pharmaceutical industry for the development of various drug candidates. It also finds applications in the synthesis of organic semiconductors for solar cells and sensors, contributing to the advancements in optoelectronics and sensor technology.
What precautions should be taken when handling ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate (CAS: 885271-93-2)?
When handling ethyl 2-(5-fluoro-1H-indazol-3-yl)acetate (CAS: 885271-93-2), appropriate personal protective equipment (PPE) should be worn, including gloves, safety glasses, and a lab coat. Storage should be in a cool, well-ventilated area away from direct sunlight. Fume hoods should be used during handling to minimize exposure. In case of a spill, clean up using appropriate absorbent materials and follow standard laboratory safety procedures. For detailed information, refer to the Safety Data Sheet (SDS).
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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