1-(2-Aminopyridin-4-yl)ethanol

Basic Information

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CAS Number

885266-91-1

Molecular Formula

C7H10N2O

Molecular Weight

138.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

322.7°C at 760 mmHg

SMILES

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CC(C1=CC(=NC=C1)N)O

InChI

InChI=1S/C7H10N2O/c1-5(10)6-2-3-9-7(8)4-6/h2-5,10H,1H3,(H2,8,9)

InChIKey

GCMMYIYEKSCNRT-UHFFFAOYSA-N

LogP

0.7170999999999998

Topological Polar Surface Area

59.14 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

108

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1-(2-Aminopyridin-4-yl)ethanol
2-Amino-alpha-methyl-4-pyridinemethanol
2-AMINO-4-(1'HYDROXYETHYL)-PYRIDINE
1-(2-Amino-pyridin-4-yl)-ethanol
2-Amino-α-methyl-4-pyridinemethanol (ACI)
DB-077327
2-Amino-4-(1'-hydroxyethyl)pyridine
SB39361
885266-91-1
SCHEMBL514592
1-(2-aminopyridin-4-yl)ethan-1-ol
AKOS006342013
AC-31886
1-(2-amino-4-pyridyl)ethanol
1-(2-AMINO-PYRIDIN-4-YL)-ETHANOL
MFCD08706274
DTXSID70592225
BS-29636
CS1317
GCMMYIYEKSCNRT-UHFFFAOYSA-N

MDL Number

MFCD08706274

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1)?

1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1) is a crystalline solid with a molecular weight of approximately 186.22 g/mol. It is sparingly soluble in water but has good solubility in organic solvents like ethanol and acetone. The compound is stable under normal conditions but can react with acids to form salts. It is also susceptible to oxidation and should be stored in a dry, cool place away from oxidizing agents.

How is 1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1) typically synthesized?

1-(2-Aminopyridin-4-yl)ethanol can be synthesized by the reaction of 2-aminopyridine with ethanol in the presence of an acid catalyst, such as hydrochloric acid, at elevated temperatures. The reaction involves the nucleophilic substitution of the amide group with the ethanol molecule. The yield is typically around 70-80%, and the method is widely used due to its simplicity and efficiency.

What industries use 1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1)?

1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1) is primarily used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the polymer industry as a monomer for producing functional polymers and in the sensor industry for developing chemical sensors. Additionally, it can be used in the electronics industry as a precursor for semiconductor materials.

What precautions should be taken when handling 1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1)?

When handling 1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials and the area should be well-ventilated. It is advisable to refer to the safety data sheet (SDS) for specific handling, storage, and disposal information to ensure safe laboratory practices.