Compound Q&A

How is 1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1) typically synthesized?

Answer

1-(2-Aminopyridin-4-yl)ethanol
1-(2-Aminopyridin-4-yl)ethanol can be synthesized by the reaction of 2-aminopyridine with ethanol in the presence of an acid catalyst, such as hydrochloric acid, at elevated temperatures. The reaction involves the nucleophilic substitution of the amide group with the ethanol molecule. The yield is typically around 70-80%, and the method is widely used due to its simplicity and efficiency.

About

English Name 1-(2-Aminopyridin-4-yl)ethanol
Molecular Formula C7H10N2O
Molecular Weight 138.17000000000002 g/mol
SMILES CC(C1=CC(=NC=C1)N)O
InChIKey GCMMYIYEKSCNRT-UHFFFAOYSA-N
Last Updated: 2025-12-25 22:28

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