1-(2-Aminopyridin-4-yl)ethanol(CAS: 885266-91-1)

1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1) is a crystalline solid with a molecular weight of approximately 186.22 g/mol. It is sparingly soluble in water but has good solubility in organic solvents like ethanol and acetone. The compound is stable under normal conditions but can react with acids to form salts. It is also susceptible to oxidation and should be stored in a dry, cool place away from oxidizing agents.

1-(2-Aminopyridin-4-yl)ethanol can be synthesized by the reaction of 2-aminopyridine with ethanol in the presence of an acid catalyst, such as hydrochloric acid, at elevated temperatures. The reaction involves the nucleophilic substitution of the amide group with the ethanol molecule. The yield is typically around 70-80%, and the method is widely used due to its simplicity and efficiency.

1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1) is primarily used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the polymer industry as a monomer for producing functional polymers and in the sensor industry for developing chemical sensors. Additionally, it can be used in the electronics industry as a precursor for semiconductor materials.

When handling 1-(2-Aminopyridin-4-yl)ethanol (CAS: 885266-91-1), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials and the area should be well-ventilated. It is advisable to refer to the safety data sheet (SDS) for specific handling, storage, and disposal information to ensure safe laboratory practices.