3-Bromo-5-fluoro-2(1H)-pyridinone

Basic Information

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CAS Number

884494-94-4

Molecular Formula

C5H3BrFNO

Molecular Weight

191.99 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

SMILES

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C1=C(C(=O)NC=C1F)Br

InChI

InChI=1S/C5H3BrFNO/c6-4-1-3(7)2-8-5(4)9/h1-2H,(H,8,9)

InChIKey

UPHUCWCSEZGVJO-UHFFFAOYSA-N

LogP

1.2764999999999997

Topological Polar Surface Area

32.86 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

209

Synonyms & References

English

CS-16756
UPHUCWCSEZGVJO-UHFFFAOYSA-N
884494-94-4
3-Bromo-5-fluoro-2-hydroxypyridine
SCHEMBL20637043
J-512020
3-Bromo-5-fluoro-2-hydroxypyrdine
SY128185
3-BROMO-5-FLUOROPYRIDIN-2-OL
2-Bromo-5-Fluoro-2-Hydroxypyridine
3-Bromo-5-fluoropyridin-2(1H)-one
MFCD08277253
SB39351
3-Bromo-5-fluoro-2-pyridinone
2-Hydroxy-3-bromo-5-fluoropyridine
FT-0659359
SCHEMBL950695
WLZ3068
AKOS005257246
CS-0102949
3-bromo-5-fluoro-1H-pyridin-2-one
DTXSID80654560
AKOS006294853
2-BROMO-5-FLUORO-2-HYDROXYPYRIDINE
3-Bromo-5-fluoropyridin-2-ol
3-Bromo-5-fluoro-2(1H)-pyridinone (ACI)
3-Bromo-5-fluoro-1H-pyridin-2-one

MDL Number

MFCD06659480

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-Bromo-5-fluoro-2(1H)-pyridinone (CAS: 884494-94-4)?

3-Bromo-5-fluoro-2(1H)-pyridinone is a crystalline solid with a molecular weight of approximately 228.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and acetone. This compound is moderately reactive towards nucleophiles and electrophiles. It exhibits good stability under normal conditions but requires protection from moisture and light to prevent hydrolysis.

How is 3-Bromo-5-fluoro-2(1H)-pyridinone (CAS: 884494-94-4) typically synthesized?

3-Bromo-5-fluoro-2(1H)-pyridinone can be synthesized through a bromination reaction of 5-fluoropyridine with N-bromosuccinimide (NBS) in the presence of a suitable initiator like benzoyl peroxide. This process yields the product with good selectivity and a moderate yield of approximately 70-80%. The reaction is conducted under anhydrous conditions to avoid side reactions.

What industries use 3-Bromo-5-fluoro-2(1H)-pyridinone (CAS: 884494-94-4)?

3-Bromo-5-fluoro-2(1H)-pyridinone is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various medicinal compounds and is also used in the development of sensors and materials due to its unique chemical properties. Its applications in polymers and semiconductors are also being explored.

What precautions should be taken when handling 3-Bromo-5-fluoro-2(1H)-pyridinone (CAS: 884494-94-4)?

When handling 3-Bromo-5-fluoro-2(1H)-pyridinone, it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat. The compound should be handled in a well-ventilated area or under a fume hood to minimize inhalation risks. Spills should be immediately cleaned up using absorbent materials, and the area should be flushed with water. It is advisable to consult the Safety Data Sheet (SDS) for more detailed information on handling and storage procedures.