Compound Q&A
How is 3-Bromo-5-fluoro-2(1H)-pyridinone (CAS: 884494-94-4) typically synthesized?
Answer
3-Bromo-5-fluoro-2(1H)-pyridinone can be synthesized through a bromination reaction of 5-fluoropyridine with N-bromosuccinimide (NBS) in the presence of a suitable initiator like benzoyl peroxide. This process yields the product with good selectivity and a moderate yield of approximately 70-80%. The reaction is conducted under anhydrous conditions to avoid side reactions.
About
CAS No
884494-94-4
English Name
3-Bromo-5-fluoro-2(1H)-pyridinone
Molecular Formula
C5H3BrFNO
Molecular Weight
191.99 g/mol
SMILES
C1=C(C(=O)NC=C1F)Br
InChIKey
UPHUCWCSEZGVJO-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16
