2,6-Dibromo-4-(trifluoromethoxy)aniline

Basic Information

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CAS Number

88149-49-9

Molecular Formula

C7H4Br2F3NO

Molecular Weight

334.92 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

70-74 ºC

Boiling Point

253.8℃ at 760 mmHg

Density

2.0±0.1 g/cm3

Flash Point

107.3℃

Refractive Index

1.557

Vapor Pressure

0.0±0.5 mmHg at 25°C

SMILES

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C1=C(C=C(C(=C1Br)N)Br)OC(F)(F)F

InChI

InChI=1S/C7H4Br2F3NO/c8-4-1-3(14-7(10,11)12)2-5(9)6(4)13/h1-2H,13H2

InChIKey

JBSWOEGXMADXOU-UHFFFAOYSA-N

LogP

3.6924

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

190

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2,6-Dibromo-4-(trifluoromethoxy)aniline
3,5-Dibromo-4-Amino Trifluoromethoxy Benzene
2,6-Dibromo-4-trifluoromethoxyaniline
2,6-Dibromo-4-(trifluoromethoxy)benzenamine
3,5-Dibromo-4-Aminotrifluoromethoxy
3,5-dibromo-5-AminoTrifluoromethoxybenzene
3.5-Dibromo-4-Aminotrifluoromethoxybenzen
4-Amino-3,5-dibromotrifluoromethoxybenzene
4-trifluoromethoxy-2,6-dibromoaniline
2-Amino-1,3-dibromo-5-(trifluoromethoxy)benzene
3,5-Dibromo-4-aminotrifluoromethoxybenzene
BROMO RILUZOLE IMPURITY
Benzenamine, 2,6-dibromo-4-(trifluoromethoxy)-
2,6-Dibromo-4-Trifluoro-Methoxy aniline
2,6-dibromo-4-trifluoromethoxy aniline
2,6Dibromo-4-(trifluoromethoxy)aniline
PubChem10031
C7H4Br2F3NO
KSC496O5L
2,6-Dibromo-4-(trifluoromethoxy)benzenamine (ACI)
2,6-dibromo-4-(trifluoromethoxy)aniline
SCHEMBL968221
EQF477YZ64
2,6-dibromo-4-(trifluoro-methoxy)ani-line
SY016225
D3038
DTXSID10371612
AKOS015854757
2,6-dibromo-4-trifluoromethoxy-aniline
2,6-dibromo-4-(trifluoromethoxy)benzenamine
3,5-dibromo-4-aminotrifluoromethoxybenzene

MDL Number

MFCD00153113

FAQ

What are the physical and chemical properties of 2,6-Dibromo-4-(trifluoromethoxy)aniline (CAS: 88149-49-9)?

2,6-Dibromo-4-(trifluoromethoxy)aniline is a crystalline compound with a molecular weight of approximately 434.01 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetonitrile. It is moderately reactive, particularly towards nucleophiles and reducing agents. The compound shows good stability under normal conditions but its reactivity can increase under certain conditions such as high temperature or in the presence of moisture.

How is 2,6-Dibromo-4-(trifluoromethoxy)aniline (CAS: 88149-49-9) typically synthesized?

2,6-Dibromo-4-(trifluoromethoxy)aniline is typically synthesized through the reaction of 2,6-dibromoaniline with trifluoromethanol in the presence of a suitable base, such as sodium hydride. The reaction involves the nucleophilic substitution of the bromine atoms by trifluoromethoxy groups. The yield can be improved by careful control of reaction conditions, including temperature and solvent choice.

What industries use 2,6-Dibromo-4-(trifluoromethoxy)aniline (CAS: 88149-49-9)?

2,6-Dibromo-4-(trifluoromethoxy)aniline is utilized in various industries, particularly in the pharmaceutical sector for the synthesis of active pharmaceutical ingredients. It is also used in the polymer industry to modify the properties of polymers. Additionally, it has applications in sensor technology and as a precursor for semiconductor materials.

What precautions should be taken when handling 2,6-Dibromo-4-(trifluoromethoxy)aniline (CAS: 88149-49-9)?

When handling 2,6-Dibromo-4-(trifluoromethoxy)aniline, it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a laboratory coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using appropriate methods and materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.