Compound Q&A
How is 2,6-Dibromo-4-(trifluoromethoxy)aniline (CAS: 88149-49-9) typically synthesized?
Answer
2,6-Dibromo-4-(trifluoromethoxy)aniline is typically synthesized through the reaction of 2,6-dibromoaniline with trifluoromethanol in the presence of a suitable base, such as sodium hydride. The reaction involves the nucleophilic substitution of the bromine atoms by trifluoromethoxy groups. The yield can be improved by careful control of reaction conditions, including temperature and solvent choice.
About
CAS No
88149-49-9
English Name
2,6-Dibromo-4-(trifluoromethoxy)aniline
Molecular Formula
C7H4Br2F3NO
Molecular Weight
334.917 g/mol
SMILES
C1=C(C=C(C(=C1Br)N)Br)OC(F)(F)F
InChIKey
JBSWOEGXMADXOU-UHFFFAOYSA-N
Last Updated: 2025-09-08 00:42
