2-Bromo-4-(1-piperidinylmethyl)pyridine

Basic Information

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CAS Number

88046-02-0

Molecular Formula

C11H15BrN2

Molecular Weight

255.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

331 ºC

Density

1.377

Flash Point

154 ºC

Refractive Index

1.58

SMILES

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C1CCN(CC1)CC2=CC(=NC=C2)Br

InChI

InChI=1S/C11H15BrN2/c12-11-8-10(4-5-13-11)9-14-6-2-1-3-7-14/h4-5,8H,1-3,6-7,9H2

InChIKey

ZTUBSWOWTOUXJJ-UHFFFAOYSA-N

LogP

2.830000000000001

Topological Polar Surface Area

16.130000000000003 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

169

Synonyms & References

English

pyridine, 2-bromo-4-(1-piperidinylmethyl)-
CS-0158828
2-Bromo-4-(piperidin-1-ylmethyl)pyridine
SCHEMBL840568
2-Bromo-4-[(piperidin-1-yl)methyl]pyridine
DTXSID10546363
2-bromo-4-piperidin-1-ylmethyl-pyridine
2-bromo-4-(1-piperidinylmethyl) pyridine
2-bromo-4-(1-piperidinomethyl)pyridine
88046-02-0
2-bromo-4-((piperidin-1-yl)methyl)pyridine
2-bromo-4-(piperidinomethyl)pyridine
AKOS015965221
2-Bromo-4-(1-piperidinylmethyl)pyridine
FT-0738270
A1-12610
ZTUBSWOWTOUXJJ-UHFFFAOYSA-N
2-BROMO-4-(1-PIPERIDINOMETHYL)PYRIDINE
2-bromo-4-(1-piperidinylmethyl)Pyridine
2-BROMO-4-(1-PIPERIDINYLMETHYL)PYRIDINE HCl
Pyridine,2-bromo-4-(1-piperidinylmethyl)-
pyridine,2-bromo-4-(1-piperidinylmethyl)
ZLD0411

MDL Number

MFCD07787467

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Bromo-4-(1-piperidinylmethyl)pyridine (CAS: 88046-02-0)?

2-Bromo-4-(1-piperidinylmethyl)pyridine is a solid with a crystalline form. Its molecular weight is approximately 261.14 g/mol. This compound has limited water solubility but is more soluble in organic solvents like dimethylformamide (DMF) and acetonitrile. It is moderately reactive with strong nucleophiles and acidic conditions. The compound is stable under normal laboratory conditions but should be stored in a dry, cool place to prevent degradation.

How is 2-Bromo-4-(1-piperidinylmethyl)pyridine (CAS: 88046-02-0) typically synthesized?

2-Bromo-4-(1-piperidinylmethyl)pyridine is typically synthesized through the reaction of 4-(1-piperidinylmethyl)pyridine with bromine in the presence of a catalyst like iron(III) bromide. The reaction is performed under anhydrous conditions to improve selectivity and yield. The product is usually purified by recrystallization from hot ethanol followed by vacuum drying.

What industries use 2-Bromo-4-(1-piperidinylmethyl)pyridine (CAS: 88046-02-0)?

2-Bromo-4-(1-piperidinylmethyl)pyridine is used in pharmaceutical research for its potential as a precursor in the synthesis of new drugs. It may also find applications in the development of certain sensors and semiconductors due to its unique chemical properties. However, its specific industrial uses are still being explored.

What precautions should be taken when handling 2-Bromo-4-(1-piperidinylmethyl)pyridine (CAS: 88046-02-0)?

When handling 2-Bromo-4-(1-piperidinylmethyl)pyridine, users should wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The compound should be stored in a well-ventilated area and handled in a fume hood to minimize exposure. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. For detailed information, refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS).